03243nam a22003734u 450000100220000000300060002200500170002800700150004500800410006002000300010102400310013104100080016224500980017025000060026826000160027426400160029030000120030633600260031833700260034433800360037034700210040634700080042752018990043565000480233465000250238265000430240770000310245070000270248177600360250885600640254485601020260885601420271099900170285210.1002/9783527831326Wiley20251030120303.0cr nn 008mam|a230925t2023||||xxu fs| |0|| 0|eng|| a9783527831326qelectronic7 a10.1002/97835278313262doi aeng00aCarbohydrate‐Based Therapeuticsh[electronic resource]cEdited by Roberto Adamo, Luigi Lay. a1 bWileyc2023 1bWileyc2023 a416pp.; atextbtxt2rdacontent acomputerbc2rdamedia aonline resourcebcr2rdacarrier atext file2rdaft bPDF aCarbohydrate-Based Therapeutics Comprehensive resource summarizing opportunities and latest progress in design methodologies for carbohydrate-based therapeutics through a disease-oriented approach Carbohydrate-Based Therapeutics covers current progress and explores new frontiers in carbohydrate-based therapeutic applications, utilizing a unique approach by providing a detailed background of diseases coupled with subsequent carbohydrate-based therapies. The link between chemistry and design of novel carbohydrate-based medicines is highlighted and a broad overview of all the potential applications of carbohydrates is given. Emphasis is laid on concepts used for carbohydrate drug design, structure- activity relationship, and impact on health and diseases. The text also discusses newer topics like nanoparticles, material science, and tissue generation. Carbohydrate-Based Therapeutics includes information on: Antimicrobial carbohydrate-based therapies, covering antibacterial and antiviral vaccines, antifungal therapies, anti-influenza therapeutics, and antiadhesive carbohydrates and glycomimetics Anti-cancer carbohydrate-based therapies, covering cancer vaccines and immunotherapy, and carbohydrate tools in cancer biology Carbohydrate-based therapies in metabolic, neuronal, and immune disorders, covering carbohydrate-based therapeutics for lysosomal disorders and neurodegenerative diseases New frontiers in carbohydrate-based therapies, covering carbohydrates for tissue engineering, antiangiogenic and regenerative medicine Providing comprehensive coverage of foundational knowledge on the subject in a unique and highly accessible format while also exploring the state of the art in the field's applications, Carbohydrate-Based Therapeutics is an essential resource for medicinal, pharmaceutical, and organic chemists, chemists in industry, biochemists, and biotechnologists. 4aPharmaceutical & Medicinal Chemistry991083 4aBioorganic Chemistry 4aBiochemistry (Chemical Biology)9910821 aAdamo, Roberto4edt9911941 aLay, Luigi4edt99119508iPrinted edition:z978352734870140uhttps://doi.org/10.1002/9783527831326aWiley Online Library40uhttps://onlinelibrary.wiley.com/action/showBook?doi=10.1002%2F9783527831326aWiley Online Library423Cover Imageuhttps://onlinelibrary.wiley.com/cms/asset/940529dd-e8b4-4de8-b317-203c97f6efab/9783527831326.cover.gifaWiley Online Library c66886d66886