02574nam a22003974u 4500 10.1002/9781394299096 Wiley 20251030120307.0 cr nn 008mam|a 240702t2024||||xxu fs| |0|| 0|eng|| 9781394299096 electronic 10.1002/9781394299096 doi eng Kirkiacharian, Serge aut 91494 Enzymes and Drugs [electronic resource] Serge Kirkiacharian, Julien Dumond 1 Wiley 2024 Wiley 2024 224pp.; text txt rdacontent computer c rdamedia online resource cr rdacarrier text file rdaft PDF Enzyme dysfunction, an essential catalyst for the smooth running of biochemical reactions and the maintenance of vital processes, is at the root of many pathologies that have paved the way for the development of numerous drugs. Aimed at pharmacists, biologists, biochemists, doctors, veterinarians, medicinal chemists and students from a wide range of disciplines, Enzymes and Drugs brings together, for the first time, extensive documentation highlighting the relationships between a large number of drugs and enzymes. The book also highlights new prospects for therapeutic discoveries offered by enzyme targeting. Numerous applications have been developed thanks to strategies for studying enzyme inhibition or activation, as well as the development of allosteric effectors, presented with their advantages and disadvantages. Various rare diseases, known as "orphan" diseases, have resulted from enzyme deficiency or absence. For their treatment, the introduction of substitute enzymes has led to major therapeutic advances. Biochemistry (Chemical Biology) 91082 Drug Formulation & Delivery 91495 Enzymes & Receptors 91496 enzyme dysfunction; biochemical reactions; drug science; enzyme targeting; enzyme inhibition; enzyme activation; rare diseases; substitute enzymes Dumond, Julien aut 91497 Printed edition: 9781786309396 https://doi.org/10.1002/9781394299096 Wiley Online Library https://onlinelibrary.wiley.com/action/showBook?doi=10.1002%2F9781394299096 Wiley Online Library Cover Image https://onlinelibrary.wiley.com/cms/asset/7ca44103-0da4-471c-9a5b-7f2a9171a632/9781394299096.cover.gif Wiley Online Library 66976 66976