03818nam a22003854u 4500 10.1002/9781394274086 Wiley 20251030120310.0 cr nn 008mam|a 240826t2024||||xxu fs| |0|| 0|eng|| 9781394274086 electronic 10.1002/9781394274086 doi eng Demetzos, Costas aut 91721 Nanotechnology in Therapeutics Basics and Trends [electronic resource] Costas Demetzos 1 Wiley 2024 Wiley 2024 304pp.; text txt rdacontent computer c rdamedia online resource cr rdacarrier text file rdaft PDF Nanotechnology in Therapeutics Comprehensive reference delivering a framework to develop and assess nanosystems that provide unique advantages in biomedical applications Nanotechnology in Therapeutics explores the idea that by studying in depth the behavior of living organisms, especially the functionality of their cell membranes, we can develop and evaluate innovative bio-inspired nanosystems that are able to deliver small molecules, biomolecules like proteins, peptides, and other genetic material in terms of the production of new therapies and vaccines. The main concept promoted in this book is an integrated approach for producing new medicines following the nanotoxicity, biotoxicity, regulatory, and ethical guidelines, which are also covered in the book. The book is divided into three parts. Part A provides an introduction and a historical overview of nanotechnology. Part B delves deeper into issues relating to lipid and polymeric nanostructures in medicine. Part C presents the regulatory landscape around nanotechnology and nanomedicine, while highlighting the need to keep an eye on emerging technologies such as artificial intelligence and machine learning. Overall, this book opens up biomedical applications for previously challenging drugs and drug targets. Written by a highly qualified professor with significant pertinent research experience, Nanotechnology in Therapeutics includes discussion on: Eukaryotic cell membranes, their structural properties, and the thermodynamic payload of their lipid bilayers The DLVO (Derjaguin, Landau, Verwey and Overbeek) theory as a scientific tool for studying the stability and the behavior of nanoparticles Liposomes, lipid nanoparticles, and solid lipid nanoparticles, as well as polymeric nanoparticles, like micelles, polymersomes, and dendrimers Issues in the approval process of nanomedicines by the regulatory agencies, such as complexity, chaos, and nonlinear dynamics With comprehensive coverage of novel concepts that have the potential to transform how new medicines are designed and developed, Nanotechnology in Therapeutics is an essential resource on the subject for chemists in industry, as well as biomedical and pharmaceutical engineers. Pharmaceutical & Medicinal Chemistry 91083 Nanomedicine 64703 Pharmacology & Pharmaceutical Medicine 91316 vaccine development; covid vaccines; drug design; drug development; therapeutics; Liposomes; lipid nanoparticles; polymeric nanoparticles; micelles; polymersomes; dendrimers; nanotoxicity; biotoxicity; medicine regulation Printed edition: 9781394274055 https://doi.org/10.1002/9781394274086 Wiley Online Library https://onlinelibrary.wiley.com/action/showBook?doi=10.1002%2F9781394274086 Wiley Online Library Cover Image https://onlinelibrary.wiley.com/cms/asset/04ff20cb-0aa4-4eb1-a9f9-6ed894eabd83/9781394274086.cover.gif Wiley Online Library 67057 67057