03643nam a22003854u 450000100220000000300060002200500170002800700150004500800410006002000300010102400310013104100080016224501280017025000060029826000160030426400160032030000120033633600260034833700260037433800360040034700210043634700080045752020650046565000390253065000360256965000240260565302430262970000280287270000340290070000260293477600360296085601020299685601420309899900170324010.1002/9783527842155Wiley20251030120313.0cr nn 008mam|a231215t2024||||xxu    fs|   |0|| 0|eng||  a9783527842155qelectronic7 a10.1002/97835278421552doi  aeng00aBiomedical Applications of Extracellular Vesiclesh[electronic resource]cEdited by Zhenhua Li, Xing‐Jie Liang, Ke Cheng.  a1  bWileyc2024 1bWileyc2024  a208pp.;  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext file2rdaft  bPDF  aBiomedical Applications of Extracellular Vesicles Unique resource focusing on biomedical applications and clinical translation of extracellular vesicles in science and medicine Focusing on key points to better understand extracellular vesicles (EVs) and their development, Biomedical Applications of Extracellular Vesicles describes in detail the biogenesis of EVs, the mechanism of intercellular communication, and the treatment of various diseases of EVs and the EV-based drug delivery platforms. An application-oriented resource, the work presents rapidly newer biomedical and clinical applications of natural and engineered EVs such as drug delivery, diagnosis, prognosis monitoring, immunotherapy, and more. The first part of this book provides a basic background on EVs. Next, the book introduces the excellent therapeutic effects of EVs themselves and the underlying mechanisms, followed by how EVs from different sources were used to construct drug delivery platforms. The latest research on EVs from leading groups around the world is presented. Sample topics covered in Biomedical Applications of Extracellular Vesicles include: Biogenesis of various EVs Pros and cons of the different instrumental and methodological developments for analytical strategies applied to EVs EVs in treatment of major diseases, such as cancer, cardiovascular and respiratory diseases Current methods of engineering EVs, and a comparison of the advantages and disadvantages of each method Biomaterials, such as hydrogels, scaffolds, and microneedles, that have been developed to further enhance the therapeutic efficacy of EVs Key challenges, such as quality control, scalability, and biosafety, that limit the clinical and industrial translation of EVs Explaining in detail how extracellular vesicles are produced and engineered, along with potential applications and commercial developments of EVs in science and industry, Biomedical Applications of Extracellular Vesicles is an essential resource on the subject for chemists, cell biologists, and molecular physicists. 4aDrug Formulation & Delivery991495 4aCell & Molecular Biology991076 4aNanomedicine96470300aextracellular vesicles; biogenesis; characterization, biomedical applications; diagnosis; therapy; drug delivery; cardiovascular diseases; tissue engineering; regenerative medicine; cancer therapy; respiratory diseases; metabolic diseases1 aLi, Zhenhua4edt9670541 aLiang, Xing‐Jie4edt9918411 aCheng, Ke4edt99184208iPrinted edition:z978352735212840uhttps://onlinelibrary.wiley.com/action/showBook?doi=10.1002%2F9783527842155aWiley Online Library423Cover Imageuhttps://onlinelibrary.wiley.com/cms/asset/f1b74b27-2527-420b-8646-824b41d57af2/9783527842155.cover.gifaWiley Online Library  c67112d67112