03772nam a22003854u 450000100220000000300060002200500170002800700150004500800410006002000300010102400310013104100080016224501640017025000060033426000160034026400160035630000120037233600260038433700260041033800360043634700210047234700080049352021660050165000330266765000210270065000130272165302240273470000320295870000270299070000250301777600360304285600640307885601020314285601420324410.1002/9781119983347Wiley20251030120315.0cr nn 008mam|a230804t2023||||xxu    fs|   |0|| 0|eng||  a9781119983347qelectronic7 a10.1002/97811199833472doi  aeng00aNatural Products and their Bioactives in Antidiabetic Drug Discoveryh[electronic resource]cEdited by Kanti Bhooshan Pandey, Maitree Suttajit, Pinar Atukeren.  a1  bWileyc2023 1bWileyc2023  a352pp.;  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext file2rdaft  bPDF  aNatural Products and their Bioactives in Antidiabetic Drug Discovery Enables researchers to effectively understand and use bioactive compounds to target, prevent, and manage diabetes Natural Products and Their Bioactives in Antidiabetic Drug Discovery provides readers with an overview of recent research in new drug discovery against diabetic complications based on bioactives from NPs, bridging the gap between the public research institutes and private companies working to find drugs to treat diabetes. To aid in reader comprehension, the text includes case studies and illustrated examples in relevant chapters. Part one presents chapters on fundamental concepts of diabetes mellitus (DM) and recent drug discovery progress along with the various druggable targets and challenges. Part two covers bioactive compounds targeting Type-1 Diabetes. Part three focuses on Type-2 Diabetes. In Part four, the contributors address gestational DM prevention and management with natural compounds. Written by a global team of experts in the field, Natural Products and their Bioactives in Antidiabetic Drug Discovery covers sample topics such as: Obesity risk factor in patients with T1DM and possible role of nutritional therapy in its management Use of natural non-insulin drugs as a novel approach to enhance therapeutic outcomes against T1DM Effectiveness of functional foods in intervening the diabetic complications and realistic results in clinical trials Implementation of nanotechnology in improving the bioavailability and reducing the threshold dose of bioactive compounds Various antidiabetic mechanisms of action of different polyphenols and immunomodulatory role of NPs bioactives relevance in T1DM therapy Effects of natural products on genetics of gestational diabetes With comprehensive coverage of recent research in new drug discovery against diabetic complications based on bioactives from NPs, Natural Products and Their Bioactives in Antidiabetic Drug Discovery is an essential resource for researchers and professionals involved in drug discovery and development, health care, medicinal chemistry, phytochemistry, plant science, and toxicology. 4aDrug Discovery & Development 4aNatural Products 4aDiabetes00adiabetes milletus; diabetes drug discovery; diabetes druggable targets; diabetes challenges; bioactive compounds targeting Type-1 Diabetes; Type-2 Diabetes; diabetes prevention; diabetes management; gestational diabetes1 aPandey, Kanti Bhooshan4edt1 aSuttajit, Maitree4edt1 aAtukeren, Pinar4edt08iPrinted edition:z978111998331640uhttps://doi.org/10.1002/9781119983347aWiley Online Library40uhttps://onlinelibrary.wiley.com/action/showBook?doi=10.1002%2F9781119983347aWiley Online Library423Cover Imageuhttps://onlinelibrary.wiley.com/cms/asset/b34c2ed3-c7e9-4778-9eae-29aeef8e1db5/9781119983347.cover.gifaWiley Online Library