02319nam a22003734u 4500 10.1002/9781394264902 Wiley 20251030120317.0 cr nn 008mam|a 231229t2023||||xxu fs| |0|| 0|eng|| 9781394264902 electronic 10.1002/9781394264902 doi eng Richard, Guy‐Franck aut 92077 Function and Evolution of Repeated DNA Sequences [electronic resource] Guy‐Franck Richard 1 Wiley 2023 Wiley 2023 400pp.; text txt rdacontent computer c rdamedia online resource cr rdacarrier text file rdaft PDF The genome of a living being is composed of DNA sequences with diverse origins. Beyond single-copy genes, whose product has a biological function that can be inferred by experimentation, certain DNA sequences, present in a large number of copies, escape the most refined approaches aimed at elucidating their precise role. The existence of what 20th century geneticists had already perceived (and wrongly described as "junk DNA"!) was confirmed by the sequencing of the first complex genomes, including that of Homo sapiens. A large part of what defines a living thing is not unique, but repeated, sometimes a very large number of times, increasing in complexity with successive duplications and multiplication. Understanding and defining the many functions of this myriad of repeated sequences, as well as their evolution through natural selection, has become one of the major challenges for 21st century genomics. Biomolecules (DNA, RNA, Peptides, etc.) 91323 Molecular Biology (Life Sciences) 92078 Molecular Evolution 81053 genome; DNA; DNA sequences; genetics; single-copy genes; junk DNA; repeated DNA sequences Printed edition: 9781789451191 https://onlinelibrary.wiley.com/action/showBook?doi=10.1002%2F9781394264902 Wiley Online Library Cover Image https://onlinelibrary.wiley.com/cms/asset/c965d19f-8af5-49d2-9ad6-9da5f3c74578/9781394264902.cover.gif Wiley Online Library 67207 67207