03503nam a22003974u 4500 10.1002/9781119660699 Wiley 20251030120317.0 cr nn 008mam|a 240117t2023||||xxu fs| |0|| 0|eng|| 9781119660699 electronic 10.1002/9781119660699 doi eng Oral Bioavailability and Drug Delivery From Basics to Advanced Concepts and Applications [electronic resource] Edited by Ming Hu, Xiaoling Li. 1 Wiley 2023 Wiley 2023 928pp.; text txt rdacontent computer c rdamedia online resource cr rdacarrier text file rdaft PDF ORAL BIOAVAILABILITY AND DRUG DELIVERY Improve the performance and viability of newly-developed and approved drugs with this crucial guide Bioavailability is the parameter which measures the rate and extent to which a drug reaches a user's circulatory system depending on the method of administration. For example, intravenous administration produces a bioavailability of 100%, since the drugs are injected directly into the circulatory system; in the case of oral administration, however, bioavailability can vary widely based on factors which, if not properly understood, can result in a failure in drug development, adverse effects, and other complications. The mechanics of oral bioavailability are therefore critical aspects of drug development. Oral Bioavailability and Drug Delivery provides a comprehensive coverage of this subject as well as its drug development applications. Beginning with basic terminology and fundamental concepts, it provides a thorough understanding of the challenges and barriers to oral bioavailability as well as the possibilities for improving this parameter. The resulting book is an indispensable tool for drug development research. Oral Bioavailability and Drug Delivery readers will also find: Discussion questions in many chapters to facilitate comprehension Detailed discussion of topics including dissolution, absorption, metabolism, and more Real-world examples of methods in actions throughout Oral Bioavailability and Drug Delivery is ideal for pharmaceutical and biotechnology scientists working in drug discovery and development; researchers in chemistry, biology, pharmacology, immunology, neuroscience, and other related fields; and graduate courses in drug development and delivery. Drug Formulation & Delivery 91495 Clinical Pharmacology & Therapeutics 91176 Biochemistry (Chemical Biology) 91082 Pharmaceutics; pharmacy; drug absorption; drug dissolution; dosage form development; formulation; oral drug delivery; drug metabolism; drug excretion; clinical trials; intravenous bioavailability; silico; biopharmaceutics; drug development; pharmaceutical clinical trials; pharmaceutical research Hu, Ming edt 92110 Li, Xiaoling edt 92111 Printed edition: 9781119660651 https://doi.org/10.1002/9781119660699 Wiley Online Library https://onlinelibrary.wiley.com/action/showBook?doi=10.1002%2F9781119660699 Wiley Online Library Cover Image https://onlinelibrary.wiley.com/cms/asset/419966e1-5cf3-4547-85de-3c1cdd0671ba/9781119660699.cover.gif Wiley Online Library 67221 67221