04323nam a22004214u 4500 10.1002/9781119615583 Wiley 20251030120318.0 cr nn 008mam|a 231013t2023||||xxu fs| |0|| 0|eng|| 9781119615583 electronic 10.1002/9781119615583 doi eng Patient Centric Blood Sampling and Quantitative Bioanalysis [electronic resource] Edited by Neil Spooner, Emily Ehrenfeld, Joe Siple, Mike S. Lee. 1 Wiley 2023 Wiley 2023 400pp.; text txt rdacontent computer c rdamedia online resource cr rdacarrier text file rdaft PDF PATIENT CENTRIC BLOOD SAMPLING AND QUANTITATIVE ANALYSIS Authoritative resource providing a complete overview of patient centric blood sampling, as well as its benefits and challenges Patient Centric Blood Sampling and Quantitative Analysis focuses on the growing interest in alternative means to standard phlebotomy and analytical workflows for the collection and analysis of high-quality human biological samples for the quantitative determination of circulating drugs, their metabolites, and endogenous substances for clinical trials, routine healthcare and neonatal screening. The book clearly explains the benefits and constraints of having patients collect small volumes of blood in locations outside of a clinic (e.g at home), including: patient convenience; less invasive procedures; increased frequency of sampling; applicability to collecting samples from the young, elderly, and those in remote locations; greater frequency; and lower cost per sample. Readers will learn about approaches for successfully implementing patient centric sampling workflows in a number of scenarios, including the clinical setting and in the analytical laboratory. Edited by four recognized experts in this field, with additional specialists in the discipline enlisted to write the component chapters, enabling greater depth and detail to be added and further raising the scientific standing of the publication, Patient Centric Blood Sampling and Quantitative Analysis includes information on: Basics of patient centric blood sampling and techniques and approaches that are available and in development for the collection and analysis of the samples Science behind patient centric blood sampling and its implications regarding human healthcare and wellbeing Application areas of patient centric sampling, including drug development, clinical chemistry/pathology, therapeutic drug monitoring, and more Practical approaches to successful implementation for existing and developing purposes and workflows, and case studies to support implementation within an organization Giving the reader a broad understanding of what patient centric sampling is and where it might be applied for existing and potential future areas, Patient Centric Blood Sampling and Quantitative Analysis is an essential resource on the subject for many different types of laboratories, areas of clinical research and healthcare, including those in pharmaceutical, clinical, and research functions. Analytical Chemistry Drug Discovery & Development 91621 Clinical Pharmacology & Therapeutics 91176 blood samples; blood analysis; blood circulating drugs; blood metabolites; blood endogenous substances; blood collection; patient centricity; home sampling; analytical approaches; pre-analytical considerations; quantitation; drug analysis; bioanalysis; biomarker analysis; automation; newborn screening; pediatric care Spooner, Neil edt 92126 Ehrenfeld, Emily edt 92127 Siple, Joe edt 92128 Lee, Mike S. edt 92129 Printed edition: 9781119615552 https://doi.org/10.1002/9781119615583 Wiley Online Library https://onlinelibrary.wiley.com/action/showBook?doi=10.1002%2F9781119615583 Wiley Online Library Cover Image https://onlinelibrary.wiley.com/cms/asset/cf30a79f-b7be-40d2-a4cb-bbb55592181d/9781119615583.cover.gif Wiley Online Library 67228 67228