04277nam a22004094u 450000100220000000300060002200500170002800700150004500800410006002000300010102400310013104100080016224501530017025000060032326000160032926400160034530000120036133600260037333700260039933800360042534700210046134700080048252024610049065000250295165000400297665000480301665303230306470000300338770000330341770000270345070000290347777600360350685600640354285601020360685601420370899900170385010.1002/9781119615583Wiley20251030120318.0cr nn 008mam|a231013t2023||||xxu    fs|   |0|| 0|eng||  a9781119615583qelectronic7 a10.1002/97811196155832doi  aeng00aPatient Centric Blood Sampling and Quantitative Bioanalysish[electronic resource]cEdited by Neil Spooner, Emily Ehrenfeld, Joe Siple, Mike S. Lee.  a1  bWileyc2023 1bWileyc2023  a400pp.;  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext file2rdaft  bPDF  aPATIENT CENTRIC BLOOD SAMPLING AND QUANTITATIVE ANALYSIS Authoritative resource providing a complete overview of patient centric blood sampling, as well as its benefits and challenges Patient Centric Blood Sampling and Quantitative Analysis focuses on the growing interest in alternative means to standard phlebotomy and analytical workflows for the collection and analysis of high-quality human biological samples for the quantitative determination of circulating drugs, their metabolites, and endogenous substances for clinical trials, routine healthcare and neonatal screening. The book clearly explains the benefits and constraints of having patients collect small volumes of blood in locations outside of a clinic (e.g at home), including: patient convenience; less invasive procedures; increased frequency of sampling; applicability to collecting samples from the young, elderly, and those in remote locations; greater frequency; and lower cost per sample. Readers will learn about approaches for successfully implementing patient centric sampling workflows in a number of scenarios, including the clinical setting and in the analytical laboratory. Edited by four recognized experts in this field, with additional specialists in the discipline enlisted to write the component chapters, enabling greater depth and detail to be added and further raising the scientific standing of the publication, Patient Centric Blood Sampling and Quantitative Analysis includes information on: Basics of patient centric blood sampling and techniques and approaches that are available and in development for the collection and analysis of the samples Science behind patient centric blood sampling and its implications regarding human healthcare and wellbeing Application areas of patient centric sampling, including drug development, clinical chemistry/pathology, therapeutic drug monitoring, and more Practical approaches to successful implementation for existing and developing purposes and workflows, and case studies to support implementation within an organization Giving the reader a broad understanding of what patient centric sampling is and where it might be applied for existing and potential future areas, Patient Centric Blood Sampling and Quantitative Analysis is an essential resource on the subject for many different types of laboratories, areas of clinical research and healthcare, including those in pharmaceutical, clinical, and research functions. 4aAnalytical Chemistry 4aDrug Discovery & Development991621 4aClinical Pharmacology & Therapeutics99117600ablood samples; blood analysis; blood circulating drugs; blood metabolites; blood endogenous substances; blood collection; patient centricity; home sampling; analytical approaches; pre-analytical considerations; quantitation; drug analysis; bioanalysis; biomarker analysis; automation; newborn screening; pediatric care1 aSpooner, Neil4edt9921261 aEhrenfeld, Emily4edt9921271 aSiple, Joe4edt9921281 aLee, Mike S.4edt99212908iPrinted edition:z978111961555240uhttps://doi.org/10.1002/9781119615583aWiley Online Library40uhttps://onlinelibrary.wiley.com/action/showBook?doi=10.1002%2F9781119615583aWiley Online Library423Cover Imageuhttps://onlinelibrary.wiley.com/cms/asset/cf30a79f-b7be-40d2-a4cb-bbb55592181d/9781119615583.cover.gifaWiley Online Library  c67228d67228