02957cam a2200505 i 45000010014000000030008000140050017000220060019000390070015000580080041000730400035001140200036001490200033001850200018002180200043002360200040002790200018003190200042003370200039003790240031004180350022004490350024004710500010004950720025005050720025005300720025005550720016005801000087005962450081006832640036007643000040008003360026008403370026008663380036008925201092009285880047020206500037020676500051021046500050021556500043022058560072022488560102023209420012024229990017024349781003260073FlBoTFG20251030122232.0m     o  d        cr cnu|||unuuu240805s2025    flu    go     000 0 eng d  aOCoLC-PbengerdaepncOCoLC-P  a9781003260073q(electronic bk.)  a1003260071q(electronic bk.)  z9781032196114  a9781040124697q(electronic bk. : EPUB)  a1040124690q(electronic bk. : EPUB)  z9781032196183  a9781040124659q(electronic bk. : PDF)  a1040124658q(electronic bk. : PDF)7 a10.1201/97810032600732doi  a(OCoLC)1450930285  a(OCoLC-P)1450930285 4aRS403 7aSCIx0130202bisacsh 7aSCIx0130402bisacsh 7aMEDx0710002bisacsh 7aMMG2bicssc1 aNangia, Ashwini K.,eauthor.uUni of Hyderabad, School of Chemistry, India.99321210aSupramolecular Synthons in Crystal Engineering of Pharmaceutical Properties. 1aBoca Raton :bCRC Press,c2025.  a1 online resource (xvi, 182 pages).  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  aThis comprehensive resource skillfully consolidates crystal engineering, the design of organic solids, and supramolecular synthons (i.e., structural hydrogen bond units) to achieve desired pharmaceutical properties, including solubility, dissolution, bioavailability, permeability, particle size, tableting, hydration, and mechanical strength. Covering 30 years of crystal engineering developments and pharmaceutical applications, this book will be a single and complete resource for supramolecular and structural chemists, the crystal engineering community, pharmaceutical scientists, and industrial researchers. Key Features Covers the fundamentals of crystal engineering and supramolecular synthons. Details the challenges of low solubility and low permeability facing oral drug formulations. Explains how heterosynthons provide a rational approach to address and implement solutions. Provides case studies from academic and industrial labs to walk the reader through the actual steps. Explores developments in the scale up and manufacture of crystal forms in pharmaceutical industry.  aOCLC-licensed vendor bibliographic record. 0aPharmaceutical chemistry.967843 7aSCIENCE / Chemistry / Clinical2bisacsh993213 7aSCIENCE / Chemistry / Organic2bisacsh965039 7aMEDICAL / Pharmacology2bisacsh964250403Taylor & Francisuhttps://www.taylorfrancis.com/books/9781003260073423OCLC metadata license agreementuhttp://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf  cE-Books  c67492d67492