TY - BOOK AU - Satin,Leslie S. AU - Ben-Johny,Manu AU - Dick,Ivy E. ED - Institute of Physics (Great Britain), TI - Calcium signals: from single molecules to physiology T2 - [IOP release $release] SN - 9780750320092 AV - QP535.C2 C357 2023eb PY - 2023///] CY - Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) PB - IOP Publishing KW - SCIENCE / Life Sciences / Biophysics KW - bisacsh KW - Calcium KW - Physiological effect KW - Cellular signal transduction KW - Calcium Signaling KW - Signal Transduction KW - Biophysics KW - bicssc N1 - "Version: 202303"--Title page verso; Includes bibliographical references; 1. Introduction / Les Satin. part I. Molecules mediating calcium influx. 2. Calcium channel selectivity and permeation : function meets 3D structure / Richard W. Tsien -- 3. Structure and function of TRP channels / Gilbert Q. Martinez and Eric N. Senning -- 4. Glutamate-gated calcium currents in the central nervous system : structural determinants, regulatory mechanisms, and biological functions / Gary J. Iacobucci and Gabriela K. Popescu; part II. Calcium signaling on channels and other effectors. 5. Monitoring the dynamics of calcium signaling effectors using genetically encoded fluorescent biosensors / Yanghao Zhong, Sohum Mehta and Jin Zhang -- 6. Calcium-activated potassium channels / Alberto J. Gonzalez-Hernandez, Aravind Kshatri and Teresa Giraldez -- 7. Calcium-activated chloride channels / Alec Kittredge, Aaron P. Owji, Sara Ragi, Stephen H. Tsang, Yu Zhang and Tingting Yang; part III. Physiological roles of calcium. 8. Excitation-contraction coupling in skeletal muscle : fast Ca2+ signaling for muscle activation / Martin F. Schneider and Erick O. Hern�andez-Ochoa -- 9. Voltage-gated Ca2+ channels and excitation-secretion coupling at the synapse / Brittany Williams, Jessica R. Thomas and Amy Lee -- 10. Calcium signaling in context : case studies in endocrine cells / Patrick A. Fletcher and Arthur S. Sherman; part IV. Calcium channels in organelles. 11. Characterization of endo-lysosomal cation channels using calcium imaging / Christian Wahl-Schott, Marc Freichel, Volodymyr Tsvilovsky and Hristo Varbanov -- 12. The structural era of the mitochondrial calcium uniporter / Enrique Balderas, Salah Sommakia, David Eberhardt, Sandra Lee and Dipayan Chaudhuri; part V. Calcium channels and disease. 13. Voltage-gated calcium channelopathies / John W. Hussey, Kevin G. Herold and Ivy E. Dick -- 14. Role of dysregulated calcium in neuropsychiatric diseases / Herie Sun and Anjali M. Rajadhyaksha; Graduate students and researchers in physiology, pharmacology, or biomedical engineering; Also available in print N2 - Written by expert contributors, this much-needed book emphasizes a quantitative and comprehensive perspective to explore the many dimensions of cellular Ca2+ signalling. Leading researchers in the field of calcium signaling present key aspects of this process in cells, starting with Ca2+ entry into the cell, its uptake from the cytosol by organelles, such as the endoplasmic reticulum and mitochondria, and the actions of Ca2+ in turn on a variety of important cellular regulatory processes. This research and reference text should prove useful to a wide readership, from students to researchers at many different levels, particularly in physiology, pharmacology, or biomedical engineering. Part of Biophysical Society-IOP series UR - https://iopscience.iop.org/book/edit/978-0-7503-2009-2 ER -