07686nam a2200817 i 4500 9780750340168 IOP 20251030124213.0 m eo d cr cn |||m|||a 230502s2023 enka fob 000 0 eng d 9780750340168 ebook 9780750340151 mobi 9780750340144 print 9780750340175 myPrint 10.1088/978-0-7503-4016-8 doi (CaBNVSL)thg00083600 (OCoLC)1375639753 CaBNVSL eng rda CaBNVSL CaBNVSL R856 .O656 2023eb QT 36 OO59m 2023eb MF bicssc MED003040 bisacsh Ooi, Ean Hin, author. 96517 Model-based approaches in biomedical engineering / Ean Hin Ooi and Yeong Shiong Chiew. Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : IOP Publishing, [2023] 1 online resource (various pagings) : illustrations (some color). text rdacontent electronic isbdmedia online resource rdacarrier [IOP release $release] IPEM-IOP series in physics and engineering in medicine and biology IOP ebooks. [2023 collection] "Version: 20230401"--Title page verso. Includes bibliographical references. 1. Introduction -- 1.1. Early developments of biomedical engineering -- 1.2. Modelling in biomedical engineering -- 1.3. Modelling approaches in biomedical engineering 2. Mechanistic modelling -- 2.1. Background -- 2.2. Fundamentals of mechanistic modelling -- 2.3. Ocular heat transfer : an illustrative example -- 2.4. Important considerations in mechanistic modelling -- 2.5. Summary 3. Review of the finite element method -- 3.1. Introduction -- 3.2. Weighted residual method -- 3.3. Finite element method -- 3.4. Finite element mesh -- 3.5. Trial basis (shape) functions -- 3.6. Galerkin finite element method -- 3.7. Mesh convergence -- 3.8. Finite element method with COMSOL Multiphysics -- 3.9. Summary 4. Heat transfer in biological tissues -- 4.1. Introduction -- 4.2. Thermoregulation -- 4.3. Bioheat transfer -- 4.4. Hyperthermia -- 4.5. Thermal therapy -- 4.6. Thermal damage -- 4.7. General summary 5. Haemodynamics -- 5.1. Introduction -- 5.2. Arteries, veins, and capillaries -- 5.3. Physical properties of blood -- 5.4. Haemodynamics of a single blood vessel -- 5.5. Computational fluid dynamics in blood flow analysis -- 5.6. Blood flow in capillaries -- 5.7. General summary 6. Mass transport in biological tissues -- 6.1. Introduction -- 6.2. Fick's law of diffusion -- 6.3. Convection-diffusion equation -- 6.4. Transvascular fluid exchange -- 6.5. Interstitial fluid flow -- 6.6. Drug delivery -- 6.7. Dual porosity model -- 6.8. General summary 7. Physiological modelling and data analytics -- 7.1. Fundamentals of physiological modelling -- 7.2. Theories of model fitting and linear regression -- 7.3. Data analytics and interpretation -- 7.4. Summary 8. Glucose-insulin system -- 8.1. Human endocrine system and the pancreas -- 8.2. Glucose level regulation and diabetes mellitus -- 8.3. Model for human glucose-insulin interaction -- 8.4. Application of glucose-insulin models in regulating glucose level -- 8.5. Summary 9. Respiratory system -- 9.1. Function of the human respiratory system -- 9.2. The mechanics of breathing -- 9.3. Respiratory system models -- 9.4. Application of respiratory system models -- 9.5. Summary 10. Cardiovascular system -- 10.1. The human cardiovascular system -- 10.2. Cardiac cycle -- 10.3. Cardiovascular disease and circulatory shock -- 10.4. Cardiovascular system modelling -- 10.5. Application of the human cardiovascular system -- 10.6. Summary 11. Ethics and biosafety -- 11.1. Introduction -- 11.2. Human ethics -- 11.3. Biosafety -- 11.4. Summary -- Appendix A. Review on heat transfer. The advent of high-performance computing has benefited various disciplines including healthcare. Enhanced computational capabilities have helped biomedical engineers reach practical solutions to sophisticated and complex biophysical and physiological problems. This book addresses two leading model-based approaches, including, mechanistic modelling and physiological modelling, and their applications in biomedical engineering. Various topics in healthcare and medicine, their comprehension through ordinary and partial differential equations and their solution utilizing appropriate numerical strategy are considered. The text is divided into two parts. Part I of the book explores the concept and application of mechanistic modelling, while Part II deals with content relevant to physiological modelling. This practical guide is a key text for undergraduate students studying biomedical engineering and researchers in the field of biomedical engineering and healthcare. Part of IPEM-IOP Series in Physics and Engineering in Medicine and Biology. Undergraduate, graduate and postgraduate students who are majoring in biomedical engineering. Students from clinical and medical fields with the appropriate mathematical background may also find the book useful. Expert and novice researchers wanting to explore computational modelling in biomedical engineering. Researchers working in healthcare systems, computer aided diagnosis of diseases, universities with applied mathematics departments, research hospitals. Also available in print. Mode of access: World Wide Web. System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader. Ean Hin Ooi is an Associate Professor at Monash University Malaysia. He is an Associate Editor for the journal Computer Methods and Programs in Biomedicine and Journal of Mechanics in Medicine and Biology. He is also a technical consultant for Ascend Technologies Ltd, United Kingdom. He has published 71 refereed journal papers, 14 conference proceedings and 8 book chapters. Yeong Shiong Chiew is a Senior Lecturer at Monash University Malaysia, as well as a visiting researcher at the University of Liege, Belgium. He is an Academic Editor for Biomed Research International and BMC Pulmonary Medicine. He has published 61 refereed journal articles, and more than 100 conference papers and abstracts, largely dealing with various modelling aspects in biomedical engineering. Title from PDF title page (viewed on May 2, 2023). Biomedical engineering Mathematical models. 96518 Biomedical engineering Computer simulation. 96519 Biomedical Engineering. Models, Theoretical. 96520 Computer Simulation. Pre-clinical medicine - basic sciences. bicssc 96521 MEDICAL / Allied Health Services / Medical Technology. bisacsh 64709 Chiew, Yeong Shiong, 1984- author. 96522 Institute of Physics (Great Britain), publisher. 17702 Print version: 9780750340144 9780750340175 IOP (Series). Release 23. IPEM-IOP series in physics and engineering in medicine and biology. IOP ebooks. 2023 collection. https://iopscience.iop.org/book/mono/978-0-7503-4016-8 E-Books 68368 68368