Introduction -- Interventional heart failure cardiology -- Revisiting cardiovascular physiology -- Guyton, pressure-volume loops and regulation of cardiac output -- Filling pressures -- The left heart system -- The right heart system -- Hemodynamics to perfusion -- Inotropes and vasodilators -- Extracorporeal membrane oxygenation -- Ventricular assist devices -- What is advanced heart failure? -- The advanced heart failure – cardiogenic shock continuum -- Classification of advanced heart failure and cardiogenic shock -- Hemodynamic phenotyping of advanced heart failure and cardiogenic shock -- Hemodynamic management in the cardiogenic shock ‘journey’ (ROSE) -- Recognize and rescue -- Optimization and Stabilization -- Heart transplantation -- Durable left ventricular assist devices -- Weaning and liberation from mechanical circulatory support -- Service delivery -- Summary/Conclusion.

This book provides extensive information on the management of advanced heart failure, cardiogenic shock and mechanical circulatory support. In this regard, this book is unique in emphasizing the physiologic interaction between physician and technology, bridging the gap between theoretical physiology and its clinical application, with a focus on the practical aspects of cardiovascular physiology in advanced heart failure/cardiogenic shock, and focusing on each part of the patient’s clinical ‘journey’. Hemodynamic Physiology in Advanced Heart Failure and Cardiogenic Shock integrates complex topics in advanced heart failure and cardiogenic shock, such as the man-machine interactive physiology and the theoretical physiology-clinical application. It therefore provides an accessible resource for cardiologists, surgeons, intensivists, specialist nurses and critical care practitioners, and is also suitable for trainees and more senior clinicians with an interest in a physiology-guided approach to advanced heart failure/cardiogenic shock and mechanical circulatory support.