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040 _aEBZ
_beng
_cEBZ
020 _a9781003170143
_q(electronic bk.)
020 _a1003170145
_q(electronic bk.)
020 _a9781000544855
_q(electronic bk. ;
_qEPUB)
020 _a1000544850
_q(electronic bk. ;
_qEPUB)
020 _a9781000544848
_q(electronic bk. ;
_qPDF)
020 _a1000544842
_q(electronic bk. ;
_qPDF)
020 _z9780367765989
020 _z9780367771898
020 _z0367765985
037 _a9781003170143
_bTaylor & Francis
050 4 _aRM151
072 7 _aMED
_x009000
_2bisacsh
072 7 _aMED
_x071000
_2bisacsh
072 7 _aMED
_x072000
_2bisacsh
072 7 _aTDCW
_2bicssc
049 _aMAIN
100 1 _aArpaia, Pasquale.
_uUniversità del Sannio, Benevento, Italy.
_964063
245 1 0 _aNon-Invasive Monitoring of Transdermal Drug Delivery.
250 _aFirst edition.
264 1 _a[Place of publication not identified] :
_bCRC Press,
_c2022.
300 _a1 online resource (216 pages)
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
341 0 _atextual
_2sapdv
_3EBSCOhost
505 0 _aPart I. Background. 1. Basic Concepts. Part II. Methods and Instrumentation. 2. Measurement method for aesthetic medicine. 3. Hyaluronic acid meter. 4. Measurement method for diabetology. 5. Insulin Meter. 6. Measurement method for orthopaedics. Part III. Case Studies. 7. Aesthetics medicine. 8. Diabetology. 9. Orthopaedics.
520 _aThe book presents an innovative technology based on injection of a very weak current to trace the quantity of a drug carried immediately after the administration. The book makes the reader familiar with the technology, from the conception through the design of the instrument, up to the preliminary clinical applications. In the first chapter, the method of transdermal drug delivery and the use of impedance spectroscopy in the dermatological field are presented. The second chapter describes a screening measurement campaign aimed at proving the feasibility of the assessment method and identifying the bandwidth of interest. The prototyping, validation and characterization of an instrument to measure the amount of drug delivered (DUSM: Drug Under Skin Meter) are presented in chapter three. In the fourth chapter three experimental campaigns, based on the electrical analysis of the biological tissue behavior due to the drug delivery, are reported: (i) laboratory emulation on eggplants, (ii) ex-vivo tests on pig ears, and finally (iii) in-vivo tests on human volunteers. In the fifth chapter a behavioral model, based on Finite Elements and Partial Differential Equation, of an impedance-based measurement system for assessing the drug released under the skin, during transdermal delivering, is proposed. The last chapter is dedicated to present a campaign in order to prove the suitability for insulin therapy applications. This book is intended for biomedical engineers, biomedical engineering students, operators working in the field of biomedical instrumentation, biotechnologists, and technicians of transdermal vehiculation.
532 0 _3EBSCOhost
_a"EBSCO evaluates our products based on the Web Content Accessibility Guidelines (WCAG) and the related Section 508 and EN 301 549 regulations in the US and EU. Most EBSCO products are substantially conformant with WCAG 2.2 level AA." Source: https://connect.ebsco.com/s/article/EBSCO-VPATs?language=en_US. Last accessed April 22, 2025.
545 0 _aPasquale Arpaia is Team Leader at European Organization for Nuclear Research (CERN). Umberto Cesarois currently an Adjunct Professor and a Graduate Engineer with the University of Naples Federico II. Nicola Moccaldi is a Research Fellow with CRdC Tecnologie Scarl, Naples, Italy. Isabella Sannino works at Cranfield University (England) in Mechatronic Laboratory of Advanced Vehicle Engineering Centre focusing on driver's neuromuscular dynamics.
588 0 _aVendor-supplied metadata.
504 _aIncludes bibliographical references and index.
650 0 _aTransdermal medication.
_964064
650 2 _aAdministration, Cutaneous
_964065
650 7 _aMEDICAL
_xBiotechnology.
_2bisacsh
_964066
650 7 _aMEDICAL
_xPharmacology.
_2bisacsh
_964067
650 7 _aMEDICAL
_xPharmacy.
_2bisacsh
_964068
700 1 _aCesaro, U.
_q(Umberto)
_964069
700 1 _aMoccaldi, N.
_q(Nicola)
_964070
700 1 _aSannino, Isabella
_964071
776 0 8 _cOriginal
_z0367765985
_z9780367765989
856 4 0 _3EBSCOhost
_uhttps://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=3033870
938 _aYBP Library Services
_bYANK
_n17632573
938 _aYBP Library Services
_bYANK
_n302725395
938 _aEBSCOhost
_bEBSC
_n3033870
994 _a92
_bN$T
999 _c55911
_d55911