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020 _a9783031379369
_9978-3-031-37936-9
024 7 _a10.1007/978-3-031-37936-9
_2doi
050 4 _aQH607-607.2
072 7 _aPSC
_2bicssc
072 7 _aSCI072000
_2bisacsh
072 7 _aPSC
_2thema
245 1 0 _aSyncytia: Origin, Structure, and Functions
_h[electronic resource] /
_cedited by Malgorzata Kloc, Ahmed Uosef.
250 _a1st ed. 2024.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2024.
300 _aX, 485 p. 81 illus., 70 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aResults and Problems in Cell Differentiation,
_x1861-0412 ;
_v71
505 0 _aPart I. Germline Syncytia, Evolution, Function, and Structure -- Chapter 1. The Ancient Origin and Function of Germline Cysts -- Chapter 2. Female Germline Cysts in Animals: Evolution and Function -- Chapter 3. Germline and Somatic Cell Syncytia in Insects -- Part II. Syncytia in Embryogenesis and Development -- Chapter 4. Reshaping the Syncytial Drosophila Embryo with Cortical Actin Networks: Four Main Steps of Early Development -- Chapter 5. Cell-Mediated Branch Fusion in the Drosophila Trachea -- Chapter 6. Trophoblast Syncytialization: A Metabolic Crossroads -- Chapter 7. Early Syncytialization of the Ovine Placenta Revisited -- Chapter 8. Syncytia in Utricularia: Origin and Structure -- Part III. Fungal and Somatic Cell Syncytia and Genomic View of Extremophiles as the Ancestral Precursors of Eukaryotic Syncytia -- Chapter 9. Syncytial Assembly Lines: Consequences of Multinucleate Cellular Compartments for Fungal Protein Synthesis -- Chapter 10. Ancestors in The Extreme: A Genomics View of Microbial Diversity in Hypersaline Aquatic Environments -- Chapter 11. Somatic Cell Fusion in Host Defense and Adaptation -- Chapter 12. Osteoclasts at Bone Remodeling: Order from Order -- Chapter 13. Muscle Progenitor Cell Fusion in the Maintenance of Skeletal Muscle -- Part IV. Virus- and Parasite- Induced Syncytia -- Chapter 14. Virus-Induced Cell Fusion and Syncytia Formation -- Chapter 15. HIV-1 Induced Cell-to-Cell Fusion or Syncytium Formation -- Chapter 16. Relevance of the Entry by Fusion at the Cytoplasmic Membrane vs. Fusion After Endocytosis in the HIV and SARS-Cov-2 Infections -- Chapter 17. Mathematical Modeling of Virus-Mediated Syncytia Formation: Past Successes and Future Directions -- Chapter 18. Syncytium Induced by Plant-Parasitic Nematodes -- Part V. Cell Fusion and Syncytia in Cancer -- Chapter 19. Mechanisms of Cell Fusion in Cancer -- Chapter 20. Cell Fusion and Syncytia Formation in Cancer -- Chapter 21. The Hallmarks of Circulating Hybrid Cells.
520 _aThis book gives a current overview on the development, origin, structure, and functions of germline and somatic cell syncytia during embryogenesis and organogenesis. It also reviews pathogen-induced syncytia and the role of syncytial cells in cancer development. The book covers the following topics: germline syncytia, evolution, function and structure; syncytia in embryogenesis and development; the role of somatic cell fusion in fungi, specialized somatic tissues, host defense and adaptation; syncytia induced by viruses and parasites; syncytia and circulating hybrid cells in cancer and other pathological conditions; It also discusses how the genomic adaptations of microorganisms to extreme habitats can prompt the evolution of mononuclear and multinucleate/syncytial cells. The book offers a fresh outlook on syncytia's role in various processes: embryogenesis, organogenesis, adaptation, host defense, and development of specialized tissues. It highlights the importance of syncytia under physiological and pathological conditions.
650 0 _aCell differentiation.
_967433
650 0 _aDevelopmental biology.
_967434
650 0 _aStem cells.
_967435
650 0 _aCytology.
_967436
650 1 4 _aCell Differentiation.
_967437
650 2 4 _aDevelopmental Biology and Stem Cells.
_967438
650 2 4 _aStem Cell Biology.
_967439
650 2 4 _aCell Biology.
_967440
700 1 _aKloc, Malgorzata.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_967441
700 1 _aUosef, Ahmed.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_967442
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031379352
776 0 8 _iPrinted edition:
_z9783031379376
776 0 8 _iPrinted edition:
_z9783031379383
830 0 _aResults and Problems in Cell Differentiation,
_x1861-0412 ;
_v71
_967443
856 4 0 _uhttps://doi.org/10.1007/978-3-031-37936-9
912 _aZDB-2-SBL
912 _aZDB-2-SXB
999 _c56603
_d56603