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020 _a9783031517129
_9978-3-031-51712-9
024 7 _a10.1007/978-3-031-51712-9
_2doi
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
072 7 _aMJCL
_2thema
245 1 0 _aProstate Cancer
_h[electronic resource] :
_bAdvancements in the Pathogenesis, Diagnosis and Personalized Therapy /
_cedited by Gordana Kocic, Jovan Hadzi-Djokic, Tatjana Simic.
250 _a1st ed. 2024.
264 1 _aCham :
_bSpringer Nature Switzerland :
_bImprint: Springer,
_c2024.
300 _aXI, 397 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aPart I: Recent advances in prostate cancer etiology and pathogenesis -- Chapter 1: Prostate cancer: Epidemiology, etiology, and prostate cancer risk factors -- Chapter 2: Genetic susceptibility to prostate cancer -- Chapter 3: Basic insights into tumor microenvironment in prostate cancer -- Chapter 4: Oxidative stress, redox signaling and apoptosis in prostate cancer development and progression -- Chapter 5: Epigenenomics, transriptomics and translational control in prostate cancer -- Chapter 6: Metabolic reprogramming as a prostate cancer hallmark -- Part II: An integrative approach in prostate cancer diagnostics -- Chapter 7: Diagnostic, prognostic and theranostic potential of miRNAs in prostate cancer -- Chapter 8: Diagnostic approaches of prostate cancer: when a biopsy is required? -- Chapter 9: Histopathological and molecular markers in assessment of prostate cancer aggressivity -- Chapter 10: Tumor markers in early detection and monitoring of prostate cancer: recent advances.-Chapter 11: Biological markers of therapeutic response in prostate cancer -- Part III: Current treatment options and monitoring of prostate cancer -- Chapter 12: Surgical treatment of prostate cancer -- Chapter 13: Robot-assisted laparoscopic radical prostatectomy -- Chapter 14: The use of apheresis in personalized cell-mediated treatment of prostate cancer -- Chapter 15: Hormone therapy for metastatic prostate cancer -- Chapter 16: Perspectives of immunotherapy for prostate cancer -- Chapter 17: Pharmacogenomics and precision therapy in prostate cancer: challenges and perspectives -- Chapter 18: Stereotactic radiotherapy in the treatment of prostate cancer -- Chapter 19: Treatment of castration-resistant prostate cancer.
520 _aThis book provides an in-depth exploration of the biology of prostate cancer, from its cellular origins to its clinical manifestations and therapeutic options. In addition to thoroughly covering a variety of diagnostic methods, radical procedures, radiation therapy, hormone therapy, and surgical techniques for prostatectomy, the book seeks to improve the understanding of the development of prostate cancer. Delving into the latest research and scientific advancements, the book starts by shedding light on the critical role of genetic susceptibility, redox signaling, apoptosis, epigenomics, transcriptomics, and metabolic reprogramming in prostate cancer development and progression. In the following section key concepts in prostate cancer diagnostics are covered. This includes the diagnostic, prognostic, and theranostic potential of miRNAs in prostate cancer; the necessity of biopsy; and the importance of histopathological and molecular markers in assessing aggressivity. It also explores recent advances in tumor markers for early detection and monitoring, as well as biological markers of therapeutic response. The book concludes by offering a wealth of knowledge on current treatment options for prostate cancer, including surgical treatments, hormone therapy for advanced cases, the use of apheresis in personalized cell-mediated treatment, pharmacogenomics and precision therapy challenges and perspectives, stereotactic radiotherapy, and treatment for castration-resistant prostate cancer. Scientists and medical professionals interested in basic and clinical research in urology and oncology will find this book to be a useful reference. It is a helpful tool for preparing medical specialization in pathology, oncology, urology, clinical biochemistry, laboratory medicine, diagnostic radiology, oncologic radiology, and related fields of cancer research. With its integrative approach to diagnostics and focus on recent scientific breakthroughs, this book empowers readers to deepen their understanding of prostate cancer and enhance their ability to advance basic and clinical research to treat this pervasive disease.
650 0 _aCancer.
_94311
650 0 _aCancer
_xTreatment.
_963722
650 0 _aCancer
_xGenetic aspects.
_973501
650 0 _aCancer
_xImaging.
_969161
650 1 4 _aCancer Biology.
_967829
650 2 4 _aCancer Therapy.
_973414
650 2 4 _aCancer Genetics and Genomics.
_973502
650 2 4 _aCancer Imaging.
_969163
700 1 _aKocic, Gordana.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_973503
700 1 _aHadzi-Djokic, Jovan.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_973504
700 1 _aSimic, Tatjana.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_973505
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031517112
776 0 8 _iPrinted edition:
_z9783031517136
776 0 8 _iPrinted edition:
_z9783031517143
856 4 0 _uhttps://doi.org/10.1007/978-3-031-51712-9
912 _aZDB-2-SBL
912 _aZDB-2-SXB
999 _c58496
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