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020 _a9783031517570
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024 7 _a10.1007/978-3-031-51757-0
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245 1 0 _aCardiac Amyloidosis
_h[electronic resource] :
_bDiagnosis and Treatment /
_cedited by Michele Emdin, Giuseppe Vergaro, Alberto Aimo, Marianna Fontana.
250 _a1st ed. 2024.
264 1 _aCham :
_bSpringer Nature Switzerland :
_bImprint: Springer,
_c2024.
300 _aVIII, 324 p. 61 illus., 56 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _a1. Tribute to Claudio Rapezzi -- 2. Giampaolo Merlini and the Pavia School -- 3. A brief history of amyloidosis -- 4. Pathophysiology, classification and epidemiology of amyloidosis -- 5. Amyloid light chain (AL) amyloidosis -- 6. Hereditary transthyretin amyloidosis -- 7. Wild-type ATTR amyloidosis -- 8. Electrocardiographic patterns -- 9. Echocardiography: a gatekeeper to diagnosis -- 10. Cardiovascular magnetic resonance: characterization of myocardial involvement -- 11. Biomarkers: monoclonal protein and indicators of cardiac damage -- 12. Plasma transthyretin and its ligands -- 13. Cardiac Scintigraphy with Bone-Avid Tracers – Old and New Applications -- 14. PET-CT: a tool for etiological diagnosis -- 15. The role of tissue biopsy: identification of the amyloid precursor and beyond -- 16. From red flags to diagnosis -- 17. Risk prediction and follow-up -- 18. Differential diagnoses in clinical mimics -- 19. Applications of Artificial Intelligence in Amyloidosis -- 20. Treatment of amyloid light-chain amyloidosis -- 21. Treatment of ATTR amyloidosis: from stabilizers to gene-editing -- 22. Treatment of cardiac complications -- 23. Monitoring disease progression and response to disease-modifying treatments -- 24. Cardiac amyloidosis: open issues and future perspectives.
520 _aCardiac amyloidosis (CA) is caused by the accumulation of amyloid fibrils in the extracellular space of the myocardium, with clinical manifestations including conduction disturbances and heart failure. CA has traditionally been considered a rare disease, lacking effective therapies and with a poor prognosis, but in recent years, increased possibilities for non-invasive diagnosis and greater awareness of the disease have led to the identification of a growing number of cases, challenging the concept of CA as a rare disease. This is why the ability to recognise and manage patients with CA should become part of the core curriculum of cardiologists, but also of internal medicine specialists, neurologists, nephrologists, haematologists, and general practitioners. This book, written by leading experts in the field, will provide the state-of-the-art in the diagnosis and management of CA and will also discuss the latest research developments and future research directions. The volume appears to be a timely one, given the great interest of clinicians and researchers in CA and the exponential increase in publications in recent year, and will be of interest to cardiologists, internal medicine and other disciplines specialists who may encounter patients with CA in their clinical practice, as well as general practitioners.
650 0 _aMedical sciences.
_965984
650 1 4 _aHealth Sciences.
_965987
700 1 _aEmdin, Michele.
_eeditor.
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700 1 _aVergaro, Giuseppe.
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700 1 _aAimo, Alberto.
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700 1 _aFontana, Marianna.
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710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031517563
776 0 8 _iPrinted edition:
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776 0 8 _iPrinted edition:
_z9783031517594
856 4 0 _uhttps://doi.org/10.1007/978-3-031-51757-0
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