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020 _a9789819983650
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024 7 _a10.1007/978-981-99-8365-0
_2doi
050 4 _aR850.A1-854
050 4 _aQH315-320
072 7 _aMBGR
_2bicssc
072 7 _aMED106000
_2bisacsh
072 7 _aMBGR
_2thema
245 1 0 _aExtracellular Vesicles
_h[electronic resource] :
_bFrom Bench to Bedside /
_cedited by Qian Wang, Lei Zheng.
250 _a1st ed. 2024.
264 1 _aSingapore :
_bSpringer Nature Singapore :
_bImprint: Springer,
_c2024.
300 _aXXII, 588 p. 77 illus., 70 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
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347 _atext file
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505 0 _aSection 1 EVs biology and function -- Classification and nomenclature of extracellular vesicles -- EVs biogenesis and function -- The mechanism of interaction between extracellular vesicles and target cells -- Biological functions of EVs in various systems -- The role and mechanism of EVs in the process of disease -- Section 2 Technologies and methods for EVs research -- Methods for EV isolation, purification and characterization -- Technologies for the analysis of EV omics -- Flow cytometry for single EV analysis -- Microfluidics-based technologies for EVs research -- Biosensing Technologies for EVs detection -- Technology for EVs surface functionalization -- Technologies for visualization and tracking of EVs -- Methods for EVs function research -- Chemical Biology Investigation of Extracellular Vesicles -- Section 3 EVs biomarker in diseases -- EV biomarker screening and clinical verification -- EVs biomarker for cancer -- EVs biomarker for disease diagnosis -- EVs biomarker for immune disorder -- EVs biomarker for neurological diseases -- EVs biomarker for infectious disease -- EVs biomarker for renal diseases -- EVs biomarker for thrombosis -- Section 4 EVs for disease therapy and prevention -- Stem cell-derived EVs for disease therapy -- EVs in cancer immunotherapy -- Platelet-derived EVs in disease therapy -- Plant-derived Extracellular Nanovesicles for Disease Therapy -- EVs engineering for therapy -- Other EVs for disease therapy -- EV-based clinical trial -- Section 5 Introduction to the guidelines and resources for EV research -- Introduction to the guidelines for EV research -- Introduction to online nucleic acid database for EV research -- Introduction of systems biology in EV.
520 _aThis book aims to provide a comprehensive and systematic understanding of research on extracellular vesicles (EVs). Extracellular vesicles, including exosomes and microvesicles, are nano-sized lipid bilayer encapsulated membranes carrying proteins, lipids, nucleic acids. They are shed by the majority of the cells into the extracellular milieu and present in many biological fluids (blood, urine, saliva, breast milk, cerebrospinal fluid, follicular fluid, semen, lung lavage, and tears). With numerous research publications in recent years, the study of EVs is the emerging field across plenty of disciplines. Many researches and efforts have shown their biogenesis, multiple roles in physiological and pathophysiological processes, and their potential roles as therapeutic agents. The book is organized by outstanding scientists in EV field from the Chinese Society for Extracellular Vesicle (CSEV). It covers the biological basic research of EVs, especially on technologies and methods, as well as the clinical application of EVs as biomarkers for disease diagnosis and therapy.
650 0 _aMedicine
_xResearch.
_962598
650 0 _aBiology
_xResearch.
_965629
650 0 _aCytology.
_967436
650 0 _aBiological transport.
_974718
650 0 _aCell membranes.
_974719
650 1 4 _aTranslational Research.
_970704
650 2 4 _aCell Biology.
_967440
650 2 4 _aMembrane Trafficking.
_974720
700 1 _aWang, Qian.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_974721
700 1 _aZheng, Lei.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_969550
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9789819983643
776 0 8 _iPrinted edition:
_z9789819983667
776 0 8 _iPrinted edition:
_z9789819983674
856 4 0 _uhttps://doi.org/10.1007/978-981-99-8365-0
912 _aZDB-2-SME
912 _aZDB-2-SXM
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