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020 _a9783031417771
_9978-3-031-41777-1
024 7 _a10.1007/978-3-031-41777-1
_2doi
050 4 _aRC346-429.2
072 7 _aMJN
_2bicssc
072 7 _aMED056000
_2bisacsh
072 7 _aMKJ
_2thema
245 1 0 _aStroke Genetics
_h[electronic resource] /
_cedited by Pankaj Sharma, James F. Meschia.
250 _a3rd ed. 2024.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2024.
300 _aXII, 624 p. 50 illus., 32 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aIntroduction -- Familial stroke epidemiology -- Association study results -- GWAS -- Aneurysms/carvernous/AVM -- ICH/amyloid/microbleeds -- CADASIL -- Fabry -- MELAS -- Sickle -- Other monogenic -- White matter disease -- Carotid atherosclerosis -- Dissection -- Pharmacogenomics -- Non-Caucasian stroke genetics -- Small vessel disease -- Genetics of neuroimaging in stroke -- Cerebrovenous thrombosis -- Ethics.
520 _aThis revised, expanded third edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed. Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics. Each chapter now contains teaching/training MCQs to help with retention of information learnt from each chapter and this will be of considerable use to those training or about to the examined in the field of inherited stroke. Additional questions via app: Download the Springer Nature Flashcards app for free and use exclusive additional material to test your knowledge.
650 0 _aNeurology .
_966816
650 0 _aInternal medicine.
650 0 _aMedical genetics.
_964976
650 1 4 _aNeurology.
_966816
650 2 4 _aInternal Medicine.
650 2 4 _aMedical Genetics.
_964976
700 1 _aSharma, Pankaj.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_974876
700 1 _aMeschia, James F.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_974877
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031417764
776 0 8 _iPrinted edition:
_z9783031417788
776 0 8 _iPrinted edition:
_z9783031417795
856 4 0 _uhttps://doi.org/10.1007/978-3-031-41777-1
912 _aZDB-2-SME
912 _aZDB-2-SXM
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