000 04194nam a22005415i 4500
001 978-981-97-0830-7
003 DE-He213
005 20251030112026.0
007 cr nn 008mamaa
008 240502s2024 si | s |||| 0|eng d
020 _a9789819708307
_9978-981-97-0830-7
024 7 _a10.1007/978-981-97-0830-7
_2doi
050 4 _aQH301-705
072 7 _aPSA
_2bicssc
072 7 _aSCI086000
_2bisacsh
072 7 _aPSA
_2thema
100 1 _aChoi, Kwang-Wook.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_976278
245 1 0 _aGenetic Studies in Model Organisms
_h[electronic resource] :
_bFrom Classical to Modern Genetics /
_cby Kwang-Wook Choi.
250 _a1st ed. 2024.
264 1 _aSingapore :
_bSpringer Nature Singapore :
_bImprint: Springer,
_c2024.
300 _aXVII, 470 p. 337 illus., 239 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aKAIST Research Series,
_x2214-255X
505 0 _aPart I. Mendel, Genetic Models, and Mutations -- Chapter 1. Mendel's Principles of Inheritance and Chromosome Theory -- Chapter 2. Genetic Model Organisms -- Chapter 3. Recombination and Chromosomal Rearrangements -- Chapter 4. Loss-of-Function Mutagenesis in Forward Genetics -- Part II. Transposons, Transgenesis, Gene Editing, and Genetic Mosaics -- Chapter 5. Non-Mendelian Genetics: Transposable elements (I) -- Chapter 6. Transposable Elements II: Insertional Mutagenesis -- Chapter 7. Gain-of-Function and Gene Silencing -- Chapter 8. Genetic Interaction, Epistasis, Modifiers -- Chapter 9. Targeted Mutagenesis -- Chapter 10. Transgenesis in Clonal Analysis -- Part III. Epigenetics, Genome Organization, and piRNA -- Chapter 11. Epigenetic Control of Gene Expression -- Chapter 12. Chromosomal Interaction in Chromatin Organization -- Chapter 13. Piwi and piRNA in Germline and Epigenetic Regulation -- Part IV. Applications of Genetic Analysis -- Chapter 14. Genetic Control of Dosage Compensation -- Chapter 15. Genetics of Programmed Cell Death -- Chapter 16. Genetics of Growth Control -- Chapter 17. Genetic Studies on Behavior.
520 _aThis book reviews key advances and new fundamentals in genetics. The increasing importance of genetic approaches in diverse areas of biology and medical sciences constantly requires in-depth information on genetic discoveries and research strategies for advanced graduate-level students as well as current researchers. This book focuses on genetic studies of various animal model systems and their major contributions to establishing modern genetics. Information covered in this book is mostly based on original research papers that extend from classical to modern genetics and applications. The contents are organized into four parts. Part I introduces fundamental concepts and experimental strategies in classical genetics. Part II discusses molecular genetics with transposons, transgenesis, clonal analysis, and gene editing technologies. Part III emphasizes epigenetic regulation of genome organization and gene expression. Part IV integrates earlier parts with landmark genetic studies on non-coding RNAs in dosage compensation, programmed cell death, growth control related to cancer, and behavioral neurobiology. .
650 0 _aBiology.
_968861
650 0 _aGenetics.
_968863
650 1 4 _aBiological Sciences.
_968865
650 2 4 _aGenetics.
_968863
650 2 4 _aGenetics and Genomics.
_968866
650 2 4 _aGenotype.
_976279
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9789819708291
776 0 8 _iPrinted edition:
_z9789819708314
776 0 8 _iPrinted edition:
_z9789819708321
830 0 _aKAIST Research Series,
_x2214-255X
_966269
856 4 0 _uhttps://doi.org/10.1007/978-981-97-0830-7
912 _aZDB-2-SBL
912 _aZDB-2-SXB
999 _c59612
_d59612