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020 _a9783031420221
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024 7 _a10.1007/978-3-031-42022-1
_2doi
050 4 _aTP248.13-.65
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100 1 _aDi Paola, Luisa.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_978146
245 1 0 _aFundamentals of Molecular Bioengineering
_h[electronic resource] /
_cby Luisa Di Paola.
250 _a1st ed. 2024.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2024.
300 _aX, 271 p. 75 illus., 63 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
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505 0 _aPart 1: Biomolecular Thermodynamics -- Chapter 1: Classical and Chemical Thermodynamics -- Chapter 2: Statistical hermodynamics -- chapter 3: Proteins -- Chapter 4: Intermolecular forces and potentials -- Chapter 5: Volumetric properties of fluids: equations of state -- Chapter 6: Biopolymers ionization and salting-out -- Chapter 7: Protein-ligand interactions and binding -- Part 2: Computational Biology -- Chapter 8: Molecular dynamics simulations for computational biology -- Chapter 9: Protein structure prediction and analysis -- Chapter 10: Systems biology and structure- based protein networks -- Chapter 11: Computational protein binding.
520 _aThis textbook covers the scientific basics of molecular bioengineering, a new field where technology meets biology and chemistry, and the fundamental knowledge required for students to understand molecular mechanisms beyond biological phenomena. The textbook focuses on the role of proteins in biomolecular machinery, and it is divided into 2 parts: Part I covers the molecular thermodynamics of biological systems, and Part II discusses the computational aspects behind protein structure prediction and molecular dynamics. In the first part of the textbook, students will find comprehensive explanations of thermodynamics and statistical mechanics, which are the basis to understand how molecular properties translate into macroscopic. Part I also offers an introduction to proteins and concepts like intermolecular forces, volumetric properties of fluids, ionization equilibria and salting-out, and protein binding and protein-protein interactions. In the second part of the textbook, students will learn about protein structure prediction and analysis, systems biology and structure-based protein networks, and computational tools and approaches for molecular dynamics simulations and protein binding and protein-protein interactions. This textbook adds to the scholarly debate with a unique contribution, addressing important new areas of biophysical chemistry and molecular biophysics not covered in currently available textbooks. Given its breadth, the textbook is suitable for courses in molecular biophysics, biochemistry, physical chemistry and bioengineering, and will also appeal to researchers and professionals in these fields. Part I of this book is a translation from its Italian original manuscript done with the help of artificial intelligence. A subsequent human revision of the content was done by the author. Springer Nature works continuously to further the development of tools for the production of books and on the related technologies to support the authors. This book is a translation of an original German edition. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation.
650 0 _aBiotechnology.
_965162
650 0 _aThermodynamics.
_966400
650 0 _aBioinformatics.
_964050
650 0 _aProteins .
_970651
650 0 _aChemistry
_xData processing.
_969913
650 0 _aBiomedical engineering.
650 1 4 _aChemical Bioengineering.
_967761
650 2 4 _aThermodynamics.
_966400
650 2 4 _aComputational and Systems Biology.
_965974
650 2 4 _aProtein Biochemistry.
_971768
650 2 4 _aComputational Chemistry.
_969915
650 2 4 _aBiomedical Engineering and Bioengineering.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031420214
776 0 8 _iPrinted edition:
_z9783031420238
776 0 8 _iPrinted edition:
_z9783031420245
856 4 0 _uhttps://doi.org/10.1007/978-3-031-42022-1
912 _aZDB-2-CMS
912 _aZDB-2-SXC
999 _c60467
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