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020 _a9789819716517
_9978-981-97-1651-7
024 7 _a10.1007/978-981-97-1651-7
_2doi
050 4 _aQD415-436
072 7 _aPSB
_2bicssc
072 7 _aSCI007000
_2bisacsh
072 7 _aPSB
_2thema
100 1 _aAgarwal, Ritu.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_978878
245 1 0 _aModeling Calcium Signaling
_h[electronic resource] :
_bA Fractional Perspective /
_cby Ritu Agarwal, Sunil Dutt Purohit, Kritika.
250 _a1st ed. 2024.
264 1 _aSingapore :
_bSpringer Nature Singapore :
_bImprint: Springer,
_c2024.
300 _aXII, 76 p. 25 illus., 23 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringerBriefs in Biochemistry and Molecular Biology,
_x2211-9361
505 0 _aChapter 1 Introduction to Fractional Calculus and Modeling -- Chapter 2 Cytosolic Calcium Distribution and Thrombin Receptor Activation -- Chapter 3 Effects of Buffers over the Cytosolic Calcium Concentration -- Chapter 4 Anomalous Subdiffusive Behaviour of Cytosolic Calcium.
520 _aThis book focuses on the fundamental processes involved in calcium signaling through fractional mathematical modeling. The intended reader of the book is mathematically proficient students of cell biology, applied mathematics and mathematical biology who are interested in learning about modeling in cell biology. The book inspires the graduate students and researchers to collaborate with experimentalists while studying the direction needed to explore the modeling literature. Organized into four chapters, the book introduces fractional calculus and is devoted to understanding the receptor activation by the ligand, that is Thrombin via fractional model incorporating the Caputo-Fabrizio fractional operator. It studies the calcium profile in red blood cells with the help of the advection-diffusion equation. The book further studies the process of buffering, aiding the lowering of the calcium concentration in the cytosol, which rises due to calcium influx from extracellular space and intracellular storage. It explains the concept of anomalous diffusion—a mathematical model is proposed to characterize the anomalous subdiffusion of cytosolic calcium.
650 0 _aBiochemistry.
_965465
650 0 _aMolecular biology.
650 0 _aCytology.
_967436
650 0 _aMathematical optimization.
_965522
650 0 _aCalculus of variations.
_967268
650 1 4 _aBiochemistry.
_965465
650 2 4 _aMolecular Biology.
650 2 4 _aCell Biology.
_967440
650 2 4 _aCalculus of Variations and Optimization.
_967270
700 1 _aPurohit, Sunil Dutt.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_978879
700 1 _aKritika.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_978880
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9789819716500
776 0 8 _iPrinted edition:
_z9789819716524
830 0 _aSpringerBriefs in Biochemistry and Molecular Biology,
_x2211-9361
_978881
856 4 0 _uhttps://doi.org/10.1007/978-981-97-1651-7
912 _aZDB-2-CMS
912 _aZDB-2-SXC
999 _c60814
_d60814