| 000 | 03612nam a22006255i 4500 | ||
|---|---|---|---|
| 001 | 978-3-031-62604-3 | ||
| 003 | DE-He213 | ||
| 005 | 20251030112627.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 240713s2024 sz | s |||| 0|eng d | ||
| 020 |
_a9783031626043 _9978-3-031-62604-3 |
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| 024 | 7 |
_a10.1007/978-3-031-62604-3 _2doi |
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| 050 | 4 | _aRM300-666 | |
| 050 | 4 | _aRM300-666 | |
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_aMMG _2bicssc |
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_aMKG _2thema |
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| 245 | 1 | 0 |
_aCNS Drug Development and Delivery _h[electronic resource] : _bConcepts and Applications / _cedited by Alan Talevi. |
| 250 | _a1st ed. 2024. | ||
| 264 | 1 |
_aCham : _bSpringer Nature Switzerland : _bImprint: Springer, _c2024. |
|
| 300 |
_aVII, 230 p. 24 illus., 22 illus. in color. _bonline resource. |
||
| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 347 |
_atext file _bPDF _2rda |
||
| 490 | 1 |
_aAAPS Introductions in the Pharmaceutical Sciences, _x2522-8358 ; _v9999 |
|
| 505 | 0 | _aChapter 1- Transporter-mediated drug delivery to the brain -- Chapter 2 - Mechanisms and methods for evaluating drug delivery via transcytosis to the brain -- Chapter 3 -In vitro blood-brain studies -- Chapter 4 - In silico prediction of CNS bioavailability -- Chapter 5 - Use of unbound exposure data to establish in vitro-in vivo correlations for CNS drug candidates -- Chapter 6 - Intranasal Delivery of Drugs to the Central Nervous System -- Chapter 7 - Polymeric nanoparticles for nose-to-brain delivery in Alzheimer's and Parkinson´s diseases -- Chapter 8 - Barriers of the CNS and their contribution to drug-resistant epilepsy -- Chapter 9 - Network-pharmacology and central nervous system drug development. | |
| 520 | _aThe book covers recent advances in the field of CNS therapeutics, including opportunities posed by expanding basic knowledge related to CNS conditions and novel approaches for efficient drug delivery to the brain (e.g., pharmaceutical nanocarriers and transporter- and transcytosis-mediated drug delivery to the brain inhibition of the blood-brain barrier). Chapters dealing with state-of-the-art in silico and in vitro tools for predictive purposes related to CNS bioavailability are also be included. This is an ideal book for undergraduate students and graduates in the field of medicine and pharmaceutics, and professionals working in the field of brain disorders. | ||
| 650 | 0 |
_aPharmacology. _967844 |
|
| 650 | 0 |
_aNeuropharmacology. _978368 |
|
| 650 | 0 | _aDrug delivery systems. | |
| 650 | 0 |
_aPharmaceutical chemistry. _967843 |
|
| 650 | 1 | 4 |
_aPharmacology. _967844 |
| 650 | 2 | 4 |
_aPharmacology. _967844 |
| 650 | 2 | 4 |
_aNeuropharmacology. _978368 |
| 650 | 2 | 4 |
_aDrug Delivery. _969429 |
| 650 | 2 | 4 |
_aPharmaceutics. _967846 |
| 700 | 1 |
_aTalevi, Alan. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt _974085 |
|
| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer Nature eBook | |
| 776 | 0 | 8 |
_iPrinted edition: _z9783031626036 |
| 776 | 0 | 8 |
_iPrinted edition: _z9783031626050 |
| 776 | 0 | 8 |
_iPrinted edition: _z9783031626067 |
| 830 | 0 |
_aAAPS Introductions in the Pharmaceutical Sciences, _x2522-8358 ; _v9999 _971123 |
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| 856 | 4 | 0 | _uhttps://doi.org/10.1007/978-3-031-62604-3 |
| 912 | _aZDB-2-SBL | ||
| 912 | _aZDB-2-SXB | ||
| 999 |
_c61567 _d61567 |
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