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020 _a9783031629839
_9978-3-031-62983-9
024 7 _a10.1007/978-3-031-62983-9
_2doi
050 4 _aRC321-580
072 7 _aPSAN
_2bicssc
072 7 _aSCI089000
_2bisacsh
072 7 _aPSAN
_2thema
245 1 0 _aEngrams
_h[electronic resource] :
_bA Window into the Memory Trace /
_cedited by Johannes Gräff, Steve Ramirez.
250 _a1st ed. 2024.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2024.
300 _aXV, 304 p. 34 illus., 32 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Neurobiology,
_x2190-5223 ;
_v38
505 0 _aSection I: Introduction -- Engrams to remember – A conversation between Johannes and Steve -- Section II: Engram cells and their mnemonic role across different brain structures -- Engrams: From behavior to brain-wide networks -- Memory storage in distributed engram cell ensembles -- Hippocampal engrams and contextual memory -- The role of prefrontal ensembles in memory across time – Time-dependent transformations of prefrontal memory ensembles -- Section III: Insights into intra-engram functioning -- All IEGs are not created equal – Molecular sorting within the memory engram -- Unveiling transcriptional and epigenetic mechanisms within engram cells: Insights into memory formation and stability -- The synaptic engram -- Section IV: Beyond associative learning: Engrams for other memory processes -- Engrams of fear memory attenuation -- Adult neurogenesis, context encoding, and pattern separation: A pathway for treating overgeneralization -- What can hippocampal engrams tell us about encoding spatial navigation? -- Understanding others’ distress through past experiences: The role of memory engram cells in observational fear -- Section V: Beyond the neurobiology of engrams -- A computational framework for memory engrams -- Engram studies: A call for historical, philosophical and sociological approaches -- If engrams are the answer, what is the question?.
520 _aThis is the first book to extensively explore the current state-of-the-art and promise of engram cells, the closest physical approximation of the memory trace to date. Converging evidence suggests that memories are stored, at least in part, as specific populations of engram cells. In this book, the leading experts in engram biology share their continuously refined insights on how engram cells contribute to information encoding and storage, across diverse brain regions and behavioral modalities. “Engrams: A Window into the Memory Trace" is broad in scope and spans molecular, cellular, circuit, computational as well as societal-philosophical aspects of memory engrams. Particular emphasis is placed on their emerging translational value for memory dysfunctions in age and stress-related disorders. .
650 0 _aNeurosciences.
_968384
650 0 _aNeuropsychology.
_972983
650 0 _aPsychobiology.
_973728
650 1 4 _aNeuroscience.
_968386
650 2 4 _aNeuropsychology.
_972983
650 2 4 _aBiological Psychology.
_980607
700 1 _aGräff, Johannes.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_980608
700 1 _aRamirez, Steve.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_980609
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031629822
776 0 8 _iPrinted edition:
_z9783031629846
776 0 8 _iPrinted edition:
_z9783031629853
830 0 _aAdvances in Neurobiology,
_x2190-5223 ;
_v38
_972663
856 4 0 _uhttps://doi.org/10.1007/978-3-031-62983-9
912 _aZDB-2-SBL
912 _aZDB-2-SXB
999 _c61616
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