000 04154nam a22006135i 4500
001 978-981-10-1941-8
003 DE-He213
005 20251030112840.0
007 cr nn 008mamaa
008 240806s2024 si | s |||| 0|eng d
020 _a9789811019418
_9978-981-10-1941-8
024 7 _a10.1007/978-981-10-1941-8
_2doi
050 4 _aQD95-96
072 7 _aPNFS
_2bicssc
072 7 _aSCI013050
_2bisacsh
072 7 _aPNFS
_2thema
100 1 _aXiao, Jianxi.
_eauthor.
_0(orcid)0000-0002-9863-572X
_1https://orcid.org/0000-0002-9863-572X
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_981980
245 1 0 _aCollagen Mimetic Peptides and Their Biophysical Characterization
_h[electronic resource] /
_cby Jianxi Xiao.
250 _a1st ed. 2024.
264 1 _aSingapore :
_bSpringer Nature Singapore :
_bImprint: Springer,
_c2024.
300 _aXV, 226 p. 108 illus., 96 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringer Series in Biomaterials Science and Engineering,
_x2195-0652 ;
_v20
505 0 _aIntroduction to collagen -- Structure of collagen triple helix -- Bioinformatics-aided Design of collagen mimic peptides -- Synthesis of collagen peptides -- CD characterization of triple helix stability -- Structural insights from X-ray crystallography -- Conformational and dynamic characterization by NMR spectroscopy -- Fluorescence detection of collagen biomarkers -- Synthesis and characterization of heterotrimeric models of collagen -- Self-assembly of collagen mimic peptides -- Concluding remarks.
520 _aThis book embarks on an enlightening journey through the molecular landscape of collagen mimic peptides, shedding light on their significance and potential. In the intricate realm of biomolecules, collagen's preeminence as the most abundant protein in the human body, forming the foundational scaffolding of tissues and organs, renders it a subject of profound scientific interest. It explores diverse facets related to collagen mimic peptides, spanning aspects such as bioinformatic analysis, synthetic strategies, pathological collagen targeting, and the construction of homotrimeric, heterotrimeric and self-assembled peptide models. Furthermore, it provides an exhaustive investigation into biophysical techniques, encompassing Circular Dichroism (CD), X-ray crystallography, Nuclear Magnetic Resonance (NMR), Fluorescence, and Raman spectroscopy, thereby empowering researchers to unravel the structural intricacies of these peptides. The book unravels the profound implications of collagen mimic peptides across a spectrum of scientific domains, including protein science, biomaterials, bioanalysis, and beyond. Its accessibility and insights cater not only to seasoned researchers but also to undergraduate and graduate students eager to delve into the complexities of this fundamental protein.
650 0 _aSpectrum analysis.
_969373
650 0 _aBiophysics.
_966239
650 0 _aBiomaterials.
650 0 _aRegenerative medicine.
_967458
650 0 _aBioorganic chemistry.
650 0 _aMaterials
_xAnalysis.
650 1 4 _aSpectroscopy.
_969375
650 2 4 _aBiophysics.
_966239
650 2 4 _aBiomaterials.
650 2 4 _aRegenerative Medicine and Tissue Engineering.
_967459
650 2 4 _aBioorganic Chemistry.
650 2 4 _aCharacterization and Analytical Technique.
_966416
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9789811019401
776 0 8 _iPrinted edition:
_z9789811019425
776 0 8 _iPrinted edition:
_z9789819776696
830 0 _aSpringer Series in Biomaterials Science and Engineering,
_x2195-0652 ;
_v20
_981981
856 4 0 _uhttps://doi.org/10.1007/978-981-10-1941-8
912 _aZDB-2-CMS
912 _aZDB-2-SXC
999 _c62276
_d62276