000 05215nam a22006375i 4500
001 978-981-97-4288-2
003 DE-He213
005 20251030112851.0
007 cr nn 008mamaa
008 240812s2024 si | s |||| 0|eng d
020 _a9789819742882
_9978-981-97-4288-2
024 7 _a10.1007/978-981-97-4288-2
_2doi
050 4 _aQH521
050 4 _aQD415-436
072 7 _aPSB
_2bicssc
072 7 _aMFGM
_2bicssc
072 7 _aSCI013040
_2bisacsh
072 7 _aPSB
_2thema
072 7 _aMFGM
_2thema
245 1 0 _aAltered Metabolism: A Major Contributor of Comorbidities in Neurodegenerative Diseases
_h[electronic resource] /
_cedited by Namita Agrawal.
250 _a1st ed. 2024.
264 1 _aSingapore :
_bSpringer Nature Singapore :
_bImprint: Springer,
_c2024.
300 _aXIII, 438 p. 60 illus., 43 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aChapter 1: An Overview of Neurodegenerative Disorders -- Chapter 2: Mechanism underlying major neurodegenerative disorders -- Chapter 3: Involvement of metabolic paradigm in progression of neurodegenerative diseases -- Chapter 4: Glial cell metabolism and neurodegenerative diseases: The current perspective -- Chapter 5: Altered glucose homeostasis in neurological disorders -- Chapter 6: Lipid Metabolism: Key Determinant in Neurodegenerative Diseases -- Chapter 7 - Dysregulated peripheral metabolism in neurodegenerative disorders -- Chapter 8- Protein Metabolism: Critical factors implicated in neurodegenerative diseases -- Chapter 9 - Altered RNA metabolism in neurodegenerative disorders -- Chapter 10: Unveiling RNA dysfunction: A key player in neurodegeneration -- Chapter 11: Emerging Relationship between the Gut Microbiota and Neurodegenerative Disorders -- Chapter 12- Signaling Pathways in Neurodegenerative diseases -- Chapter 13: An overview of imaging techniques for diagnosis of debilitating neurodegenerative diseases -- Chapter 14: Novel Metabolic Biomarkers and Therapeutic Strategies in Neurodegenerative Diseases -- Chapter 15: Phytochemicals: Promising alternatives for metabolic regulation in neurodegenerative diseases.
520 _aThis book presents a systematic and extensive understanding about metabolic alterations affecting multiple aspects of different neurodegenerative diseases (NDDs), such as Alzheimer’s, Parkinson’s, Huntington’s disease, SCAs, SBMA, DRPLA, ALS, Freidrich Ataxia etc. The book also illustrates cellular and molecular mechanisms behind the key neurodegenerative diseases and further expands on concept of unique and developing biomarkers associated with the onset and progression of NDDs. Additionally, it elaborates on the concept of latest imaging tools to monitor state of NDDs and accordingly develop therapeutic approaches entailing phytochemicals in the management of metabolic alterations associated with NDDs that ultimately suppresses course of devastating NDDs. The book aids to improve the overall understanding about the NDD and involvement of metabolic disorder as a major factor for indisposition of the disease. Therefore, suggesting that targetting metabolic variations by phytochemicals can combat NDD related symptoms for the betterment of impacted patients. While introducing cellular and molecular mechanisms and the treatment regimen under the umbrella of metabolism in several NDDs, the book covers major aspects of understanding the metabolic basis of NDDs, its implications, and treatment. This will inflate the readers' understanding about this particular area and guide those working in this domain, be it a researcher or clinicians,to choose or design effective therapeutic strategies to curb metabolic alterations linked with these disorders. This book will not only contribute towards improving the overall state of the challenged individuals but will also bring new hope towards improving the quality of lives of affected patients.
650 0 _aMetabolism.
_92468
650 0 _aNervous system
_xDiseases.
_964036
650 0 _aTherapeutics.
_970087
650 0 _aInternal medicine.
650 0 _aMedicine
_xResearch.
_962598
650 0 _aBiology
_xResearch.
_965629
650 0 _aNatural products.
650 1 4 _aMetabolism.
_92468
650 2 4 _aNeurological Disorders.
_974042
650 2 4 _aTherapeutics.
_970087
650 2 4 _aInternal Medicine.
650 2 4 _aBiomedical Research.
_965633
650 2 4 _aNatural Products.
700 1 _aAgrawal, Namita.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_982263
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9789819742875
776 0 8 _iPrinted edition:
_z9789819742899
776 0 8 _iPrinted edition:
_z9789819742905
856 4 0 _uhttps://doi.org/10.1007/978-981-97-4288-2
912 _aZDB-2-SBL
912 _aZDB-2-SXB
999 _c62421
_d62421