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020 _a9783031595677
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024 7 _a10.1007/978-3-031-59567-7
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050 4 _aQD241-441
072 7 _aPNN
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072 7 _aSCI013040
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245 1 0 _aProgress in the Chemistry of Organic Natural Products 124
_h[electronic resource] /
_cedited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch.
250 _a1st ed. 2024.
264 1 _aCham :
_bSpringer Nature Switzerland :
_bImprint: Springer,
_c2024.
300 _aVII, 233 p. 157 illus., 77 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aProgress in the Chemistry of Organic Natural Products,
_x2192-4309 ;
_v124
505 0 _aChapter 1: Natural Products Dereplication: Databases and Analytical Methods by Perez Victoria -- Chapter 2: The Chemical Ecology of Plant Natural Products by Li et al -- Chapter 3: Chemical Constituents Isolated from the Lichen Biome of Selected Species Native to North America by Rakotondraibe and Spjut.
520 _aThis volume presents three chapters discussing a range of topics. Chapter 1 deals with the development of efficient methods for compound dereplication that have been critical in the re-emergence of research on natural products as a source of new drug leads. It describes the main methods of dereplication, which rely on the combined use of large natural product databases and spectral libraries, alongside the information obtained from chromatographic, UV-Vis, MS, and NMR spectroscopic analyses of the samples of interest. Chapter 2 describes 989 plant natural products and their ecological functions in plant-herbivore, plant-microorganism, and plant-plant interactions. These compounds include alkaloids, phenols, terpenoids, and other structural types. The information presented should provide the basis for in-depth research on these plant natural products and their natural functions, and also for their further development and utilization. Chapter 3 focuses on lichens, with each constituting a symbiotic association composed of a primary mycobiont and one or more photobionts living mutualistically. Covered are lichens and their bionts, taxonomic identification, and their chemical constituents as exemplified by what is found in lichen biomes, especially those endemic to North America. Extraction and isolation procedures, as well as updates on dereplication methods using mass spectrometric GNPS and NMR spectroscopic spin network fingerprint procedures, and marker-based techniques to identify lichens are discussed. The isolation and structure elucidation of secondary metabolites of an endolichenic Penicillium species that produces bioactive compounds is described in detail.
650 0 _aNatural products.
650 0 _aPlant ecology.
650 0 _aAnalytical chemistry.
650 0 _aChemistry, Organic.
_965325
650 1 4 _aNatural Products.
650 2 4 _aPlant Ecology.
650 2 4 _aAnalytical Chemistry.
650 2 4 _aBioanalytical Chemistry.
_984826
650 2 4 _aOrganic Chemistry.
_965327
700 1 _aKinghorn, A. Douglas.
_eeditor.
_0(orcid)0000-0002-6647-8707
_1https://orcid.org/0000-0002-6647-8707
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_4http://id.loc.gov/vocabulary/relators/edt
_972463
700 1 _aFalk, Heinz.
_eeditor.
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_4http://id.loc.gov/vocabulary/relators/edt
_972464
700 1 _aGibbons, Simon.
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700 1 _aAsakawa, Yoshinori.
_eeditor.
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_1https://orcid.org/0000-0002-1847-412X
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_4http://id.loc.gov/vocabulary/relators/edt
_972466
700 1 _aLiu, Ji-Kai.
_eeditor.
_0(orcid)0000-0001-6279-7893
_1https://orcid.org/0000-0001-6279-7893
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_972467
700 1 _aDirsch, Verena M.
_eeditor.
_0(orcid)0000-0002-9261-5293
_1https://orcid.org/0000-0002-9261-5293
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_4http://id.loc.gov/vocabulary/relators/edt
_972468
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031595660
776 0 8 _iPrinted edition:
_z9783031595684
776 0 8 _iPrinted edition:
_z9783031595691
830 0 _aProgress in the Chemistry of Organic Natural Products,
_x2192-4309 ;
_v124
_972469
856 4 0 _uhttps://doi.org/10.1007/978-3-031-59567-7
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