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| 001 | 978-981-97-4864-8 | ||
| 003 | DE-He213 | ||
| 005 | 20251030113141.0 | ||
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| 008 | 241014s2024 si | s |||| 0|eng d | ||
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_a10.1007/978-981-97-4864-8 _2doi |
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| 050 | 4 | _aQH315-320 | |
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| 245 | 1 | 0 |
_aChemistry and Biology of O-GlcNAcylation _h[electronic resource] / _cedited by Wen Yi. |
| 250 | _a1st ed. 2024. | ||
| 264 | 1 |
_aSingapore : _bSpringer Nature Singapore : _bImprint: Springer, _c2024. |
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| 300 |
_aVII, 178 p. 44 illus., 39 illus. in color. _bonline resource. |
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| 336 |
_atext _btxt _2rdacontent |
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_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 347 |
_atext file _bPDF _2rda |
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| 505 | 0 | _aChapter 1. Chemical tools for decoding the functions of O-GlcNAcylation -- Chapter 2. Profiling O-GlcNAcylation with mass spectrometry -- Chapter 3. O-GlcNAcylation and cell metabolism -- Chapter 4. O-GlcNAcylation and transcriptional regulation and epigenetics -- Chapter 5. O-GlcNAcylation and signal transduction -- Chapter 6. O-GlcNAcylation and stem cells -- Chapter 7. O-GlcNAcylation and immune regulation -- Chapter 8. O-GlcNAcylation and neuronal development, neurodegeneration and neurological disorders. | |
| 520 | _aO-linked N-acetylglucosamine (O-GlcNAc) is a prevalent post-translational modification of numerous intracellular proteins. This modification has recently emerged as a key regulator of various important biological processes, including gene transcription, stress response, metabolic homeostasis, and immune regulation. Given the critical role of O-GlcNAc in normal physiology, increasing evidence has now demonstrated that deregulation of O-GlcNAc is closely associated with the development and progression of various diseases, including neurodegeneration, cardiovascular disease, and cancer. This book provides a comprehensive overview of the current progress and understanding of this modification in biology, and likely provides new research directions in the future. | ||
| 650 | 0 |
_aMedicine _xResearch. _962598 |
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| 650 | 0 |
_aBiology _xResearch. _965629 |
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_aCytology. _967436 |
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| 650 | 1 | 4 |
_aBiomedical Research. _965633 |
| 650 | 2 | 4 |
_aCell Biology. _967440 |
| 700 | 1 |
_aYi, Wen. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt _986001 |
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| 773 | 0 | _tSpringer Nature eBook | |
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_iPrinted edition: _z9789819748631 |
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_iPrinted edition: _z9789819748655 |
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