000 04389nam a22005295i 4500
001 978-3-031-66352-9
003 DE-He213
005 20251030113238.0
007 cr nn 008mamaa
008 241022s2024 sz | s |||| 0|eng d
020 _a9783031663529
_9978-3-031-66352-9
024 7 _a10.1007/978-3-031-66352-9
_2doi
050 4 _aRC705-779
072 7 _aMJL
_2bicssc
072 7 _aMED079000
_2bisacsh
072 7 _aMJL
_2thema
100 1 _aNieman, Gary F.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_986382
245 1 0 _aApplied Physiology to Reduce Ventilator Induced Lung Injury
_h[electronic resource] :
_bClinical Applications for the Acutely Injured Lung /
_cby Gary F. Nieman, Nader M. Habashi.
250 _a1st ed. 2024.
264 1 _aCham :
_bSpringer Nature Switzerland :
_bImprint: Springer,
_c2024.
300 _aIX, 191 p. 66 illus., 59 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aUnifying Hypothesis of Ventilator Induced Lung Injury -- Current Protective Ventilation Approach -- Alveolar and alveolar duct acinar mechanics in the normal lung -- Alveolar and alveolar duct mechanics in the acutely injured lung Peeling Stress and Stress Multiplication -- The Acutely Injured lung becomes Time Press Dependent -- Applied Physiologic Analysis of Clinically Tested Protective Ventilation Strategies -- It’s not the Wand it’s the Wizard It’s Not Just the Mode but the Method Used to Set and Adjust the Mode that is Lung Protective -- Novel Time Controlled Adaptive Ventilation Method to Minimize VILI -- Adaptive Dynamic Subtidal Ventilation ADSV technology Lung Protection by Millisecond Adjustments in Gas Flow Volume and Pressure at the Alveolar Level -- Epilogue.
520 _aThis book details the mechanisms of ventilator induced lung injury (VILI) at the alveolar level with the aim to identify optimal ventilation methods necessary to preserve lung function. Mortality associated with the acute respiratory distress syndrome (ARDS), including that caused by COVID-19, remains unacceptably high. The primary treatment is supportive in the form of protective mechanical ventilation, but set improperly this can cause an unintended secondary VILI significantly increasing mortality. To improve ventilation strategies needed to reduce VILI the alteration in alveolar mechanics caused by ARDS must be understood. The protective ventilation strategy must attempt to normalize alveolar mechanics, which would significantly reduce the mechanical damage subjected to lung tissue during mechanical ventilation. Written by leading experts with numerous diagrams, figures, and videos, this book takes the latest research in the field and translates it to clinical practice. Authors discuss the ARDS-induced alteration in alveolar mechanics that make it so susceptible to VILI and novel ventilation strategies necessary to normalize alveolar mechanics and reduce ARDS related morbidity and mortality. Chapters cover normal lung (alveolar mechanics and micro anatomy), how these are altered during acute lung injury, and the optimal Mechanical Breath Profile (MBp) necessary to stabilize and open the lung to reduce both VILI and acute lung injury-induced morbidity and mortality. This is an ideal guide for pulmonologists, critical care specialists, surgeons, and all medical professionals working with patients on ventilation.
650 0 _aRespiratory organs
_xDiseases.
_977494
650 0 _aCritical care medicine.
_963042
650 0 _aSurgery.
_972080
650 1 4 _aPneumology.
_977495
650 2 4 _aIntensive Care Medicine.
_973198
650 2 4 _aSurgery.
_972080
700 1 _aHabashi, Nader M.
_eauthor.
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_986383
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031663512
776 0 8 _iPrinted edition:
_z9783031663536
776 0 8 _iPrinted edition:
_z9783031663543
856 4 0 _uhttps://doi.org/10.1007/978-3-031-66352-9
912 _aZDB-2-SME
912 _aZDB-2-SXM
999 _c64376
_d64376