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020 _a9783031688119
_9978-3-031-68811-9
024 7 _a10.1007/978-3-031-68811-9
_2doi
050 4 _aQH509
050 4 _aQH601-602
072 7 _aPSF
_2bicssc
072 7 _aSCI017000
_2bisacsh
072 7 _aPSF
_2thema
245 1 0 _aExtracellular Vesicles as Matrix Messengers
_h[electronic resource] /
_cedited by Kirsi Rilla.
250 _a1st ed. 2024.
264 1 _aCham :
_bSpringer Nature Switzerland :
_bImprint: Springer,
_c2024.
300 _aXII, 296 p. 32 illus., 31 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aBiology of Extracellular Matrix,
_x2191-1959 ;
_v15
505 0 _aChapter 1. Manipulating the Matrix: Role of Extracellular Vesicles -- Chapter 2. Extracellular Matrix Remodeling in Physiological and Pathological Conditions: Insight into Extracellular Vesicles Contribution -- Chapter 3. Extracellular Matrix Modulation by Cancer-Derived Extracellular Vesicles: Impact on Cancer Malignancy -- Chapter 4. Role of Hyaluronan in Interactions of Tumor-Derived Extracellular Vesicles with Cells of Monocyte Origin -- Chapter 5. Extracellular Vesicles in Inflammation -- Chapter 6. Extracellular Vesicles in Synovial Fluid: Their role in Joint Homeostasis and Patophysiology -- Chapter 7. Extracellular Vesicles from Obese Adipose Tissue and Their Relationship with the Development of Comorbidities -- Chapter 8. Potential of Extracellular Vesicles as Therapeutics in Retinal Diseases -- Chapter 9. AFM-Based Mechanobiology of Extracellular Vesicles -- Chapter 10. Bioaffinity Recognition of Extracellular Vesicle Glycosylations -- Chapter 11. Imaging of EVs in the 3D Matrix Networks.
520 _aThe cells in our body release a wide variety of factors into the extracellular space that help to signal, regulate and build the extracellular matrix. One of the most fascinating of these factors are extracellular vesicles (EVs). These lipid membrane-covered particles have now emerged as a new powerful method of near and distant intercellular communication. EVs facilitate communication between cells and their extracellular environment, which includes solid tissues and body fluids. This volume summarizes current knowledge on EVs as integral and active components of the extracellular matrix. It covers topics such as the interplay between EVs and ECM molecules and how cancer cells modify their microenvironment by releasing EVs. Additionally, it discusses how EVs can mediate tissue repair and regeneration by modulating matrix degradation, protein cross-linking, and matrix calcification. The book explores instances where EVs play a crucial role in conditions related to matrix biology, such as cancer and arthritis, and considers their potential as therapeutic agents for these medical conditions. Both experienced researchers and clinicians, as well as PhD students who wish to study the extracellular matrix and extracellular vesicles will find this book is an excellent introduction into the field of EV biology with applications in matrix research. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.
650 0 _aBiological transport.
_974718
650 0 _aCell membranes.
_974719
650 0 _aCytology.
_967436
650 0 _aDiseases.
_968840
650 0 _aRegenerative medicine.
_967458
650 0 _aBiotechnology.
_965162
650 1 4 _aMembrane Trafficking.
_974720
650 2 4 _aCell Biology.
_967440
650 2 4 _aMechanisms of Disease.
_981824
650 2 4 _aRegenerative Medicine and Tissue Engineering.
_967459
650 2 4 _aBiotechnology.
_965162
700 1 _aRilla, Kirsi.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_987071
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031688102
776 0 8 _iPrinted edition:
_z9783031688126
776 0 8 _iPrinted edition:
_z9783031688133
830 0 _aBiology of Extracellular Matrix,
_x2191-1959 ;
_v15
_987072
856 4 0 _uhttps://doi.org/10.1007/978-3-031-68811-9
912 _aZDB-2-SBL
912 _aZDB-2-SXB
999 _c64738
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