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020 _a9789819746125
_9978-981-97-4612-5
024 7 _a10.1007/978-981-97-4612-5
_2doi
050 4 _aRC270.8
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
072 7 _aMJCL
_2thema
245 1 0 _aProstate Cancer: Molecular Events and Therapeutic Modalities
_h[electronic resource] /
_cedited by Gautam Sethi, Milad Ashrafizadeh, Nasim Ebrahimi.
250 _a1st ed. 2024.
264 1 _aSingapore :
_bSpringer Nature Singapore :
_bImprint: Springer,
_c2024.
300 _aIX, 291 p. 23 illus., 16 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aChapter 1. Anatomy and function of prostate -- Chapter 2. Epidemiology, risk factors and histopathological profile of prostate cancer -- Chapter 3. Prostate cancer and Inflammation -- Chapter 4. Prostate cancer, apoptosis, autophagy and ferroptosis: Cell death mechanisms and their crosstalk -- Chapter 5. Prostate cancer and metastasis: An emphasis on EMT mechanism -- Chapter 6. Prostate cancer and Wnt/STAT3 signaling -- Chapter 7. Prostate cancer and EZH2 signaling -- Chapter 8. Prostate cancer and PTEN/PI3K/Akt/mTOR signaling -- Chapter 9. Prostate cancer and non-coding RNAs: A focus on miRNAs, lncRNAs and circRNAs -- Chapter 10. Prostate cancer and tumor microenvironment -- Chapter 11. Chemoresistance, radioresistance and androgen-deprivation therapy resistance in prostate cancer -- Chapter 12. Plant derived-natural products in treatment of prostate cancer -- Chapter 13. Gene therapy as a new emerging strategy for prostate cancer -- Chapter 14. Nanoparticle-based therapeutic strategies in prostate cancer suppression.
520 _aThe book covers the various cell signaling pathways responsible for prostate cancer progression, conventional therapies used for prostate cancer treatment, new emerging therapeutics, and challenges in the treatment of cancer patients. It describes the different molecular pathways responsible for prostate cancer progression to improve readers' knowledge about the role of signaling networks, and cellular and molecular aspects of prostate cancer progression. These topics include mechanisms responsible for prostate cancer malignancy with a focus on molecular pathways. It also discusses the current challenges in prostate cancer treatment such as drug resistance and immune evasion and introduces novel therapeutics such as gene therapy and nanotherapeutics for prostate cancer. This book is completely novel and unique and covers all aspects of prostate cancer progression and challenges in therapy while presenting solutions. Written by prestigious researchers around the world, this book will be interesting to researchers and practitioners, especially those working in urological cancers.
650 0 _aCancer
_xTreatment.
_963722
650 0 _aMedical genetics.
_964976
650 0 _aCancer.
_94311
650 0 _aNanomedicine.
_964703
650 0 _aOncology.
_970760
650 0 _aEpidemiology.
_965983
650 0 _aGenetics
_xResearch.
_979924
650 1 4 _aCancer Therapy.
_973414
650 2 4 _aClinical Genetics.
_973305
650 2 4 _aCancer Nanotechnology.
_978154
650 2 4 _aOncology.
_970760
650 2 4 _aEpidemiology.
_965983
650 2 4 _aGenetics Research.
_979925
700 1 _aSethi, Gautam.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_988133
700 1 _aAshrafizadeh, Milad.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_988134
700 1 _aEbrahimi, Nasim.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_988135
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9789819746118
776 0 8 _iPrinted edition:
_z9789819746132
776 0 8 _iPrinted edition:
_z9789819746149
856 4 0 _uhttps://doi.org/10.1007/978-981-97-4612-5
912 _aZDB-2-SME
912 _aZDB-2-SXM
999 _c65255
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