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020 _a9789819755363
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024 7 _a10.1007/978-981-97-5536-3
_2doi
050 4 _aR850.A1-854
050 4 _aQH315-320
072 7 _aMBGR
_2bicssc
072 7 _aMED106000
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072 7 _aMBGR
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245 1 0 _aExtracellular Vesicle: Biology and Translational Application
_h[electronic resource] /
_cedited by Zongjin Li.
250 _a1st ed. 2024.
264 1 _aSingapore :
_bSpringer Nature Singapore :
_bImprint: Springer,
_c2024.
300 _aVIII, 348 p. 53 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
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505 0 _aChapter 1. Extracellular Vesicles: Tiny Packages with Big Potential -- Chapter 2. Regulation and Mechanisms of Exosome Cargo Selection and Secretion -- Chapter 3. Exosomes (Extracellular Vesicles): A Significant Mediator through Inter-organs communication in Mesenchymal Stem Cell Therapy -- Chapter 4. Extracellular vesicle isolation methods -- Chapter 5. Technologies for EV Surface Modification and Its Application in Targeted -- Chapter 6. Design of Artificial Extracellular Vesicles for Treatments of Cardiovascular Diseases -- Chapter 7. EV Tetraspanins in Regenerative Medicine -- Chapter 8. The mechanisms and applications of exosomes in dermatology -- Chapter 9. Stem cell-derived extracellular vesicles as therapeutics against renal diseases -- Chapter 10. Exosomes for ophthalmic therapeutics -- Chapter 11. The Role of Extracellular vesicles in inflammatory bowel diseases -- Chapter 12. The applications of exosomes in the treatment of autoimmune-mediated eye diseases -- Chapter 13. Extracellular Vesicles in Pregnancy: Functional Insights, Diagnostic Potential for Maternal-Fetal Disorders, and Therapeutic Implications -- Chapter 14. Extracellular vesicles in aging and age-related diseases -- Chapter 15. Extracellular vesicle imaging in theranostic applications -- Chapter 16. Extracellular vesicles: main challenges in industrialization.
520 _aThis book focuses on the applications of extracellular vesicles (EVs) for regenerative medicine. EVs are small, lipid-bound vesicles carrying cargo that can be released by virtually all cell types. Over the past decades, the field of EV research has experienced exponential growth. Once dismissed as mere cellular debris, EVs are now recognized as sophisticated messengers, facilitating the transmission of crucial information between cells and orchestrating a myriad of biological processes. Notably, stem cell-derived EVs hold particular promise in regenerative therapeutic applications. Rich in the functional components of stem cells, these EVs offer an alternative approach to cell therapy for tissue repair and regeneration. The purpose of this book is to provide an overview of EVs on their biology, function, and potential applications. The book starts with exploring the intricate biology of EVs, their cargo, and their unique ability to modulate cellular processes. It discusses the therapeutic potential of EVs in various diseases, as well as the approaches for the bionanotechnological development of artificial EVs for theranostics. Large-scale EV isolation methods and their preclinical applications are also addressed. It will be useful for undergraduate and graduate students in medicine and cell biology, biologist, and others who are interested in such topic.
650 0 _aMedicine
_xResearch.
_962598
650 0 _aBiology
_xResearch.
_965629
650 0 _aCytology.
_967436
650 0 _aTherapeutics.
_970087
650 1 4 _aTranslational Research.
_970704
650 2 4 _aCell Biology.
_967440
650 2 4 _aTherapeutics.
_970087
700 1 _aLi, Zongjin.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_988834
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
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776 0 8 _iPrinted edition:
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776 0 8 _iPrinted edition:
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856 4 0 _uhttps://doi.org/10.1007/978-981-97-5536-3
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