000 04501nam a22005895i 4500
001 978-981-97-7459-3
003 DE-He213
005 20251030114621.0
007 cr nn 008mamaa
008 241216s2024 si | s |||| 0|eng d
020 _a9789819774593
_9978-981-97-7459-3
024 7 _a10.1007/978-981-97-7459-3
_2doi
050 4 _aQH324-324.9
072 7 _aPS
_2bicssc
072 7 _aPDN
_2bicssc
072 7 _aSCI008000
_2bisacsh
072 7 _aPS
_2thema
072 7 _aPDN
_2thema
245 1 0 _aAdvances in Metabolomics
_h[electronic resource] /
_cedited by Vijai Singh.
250 _a1st ed. 2024.
264 1 _aSingapore :
_bSpringer Nature Singapore :
_bImprint: Springer,
_c2024.
300 _aXVIII, 391 p. 32 illus., 27 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _a1. Current approaches on metabolomics -- 2. Applications of computational and data sciences in metabolomics -- 3. Design of biosynthetic pathway for production of metabolites -- 4. Dissecting Cellular Heterogeneity: Single-Cell Metabolomics for Unmasking Hidden Variations -- 5. Biosensors for Detection of Metabolites -- 6. Unveiling the Molecular Fingerprint: Mass Spectrometry in Metabolomics -- 7. Utilizing HPLC for Efficient Metabolite Purification -- 8. NMR Spectroscopy for Characterisation of Metabolite -- 9. Transcriptional control for metabolite production -- 10. Microfluids in metabolites detection, production, and optimization -- 11. Cell free systems in metabolomics -- 12. Unlocking the Metabolome: A Guide to Genome Editing for Precision Control of Cellular Chemistry -- 13. Production and Fermentation Optimization of Flavour and Fragrance Molecules -- 14. Bioprocessing and Purification of Metabolites -- 15. Scaling Up Nature's Chemistry: A Guide to Industrial Production of Valuable Metabolites -- 16. Regulatory, economic and educational issues in metabolomics.
520 _aThe book delves into metabolomics which is a rapidly growing field that focuses on the study of chemical processes involving metabolites. These metabolites are small molecules that serve as substrates, intermediates, and end products of cellular metabolism. The book covers a wide range of tools and methods to facilitate metabolomics analysis, including modelling, gas chromatography, GC-MS, HPLC, MALDI, nuclear magnetic resonance, and many others. The book introduces metabolomics and then delves into tools and methods used in metabolomics research, followed by genome-scale analysis and fluxomics, which explore the complex metabolic networks within cells. The design of biosynthetic pathways is discussed in detail, highlighting their significance in manipulating cellular metabolism. The book also explores biosensors, chromatography techniques, NMR spectroscopy, transcriptional control of metabolite production, microfluidics, and the role of artificial intelligence and machine learning in metabolomics research. Additionally, it delves into cell-free systems, bioprocess optimization, fermentation technology, and industrial-scale production of metabolites. This book fills a significant gap in the market with comprehensive coverage and inclusion of diverse topics making it a valuable resource for students, researchers, scientists, clinicians, policymakers, and practitioners in the field.
650 0 _aBiology
_xTechnique.
_967845
650 0 _aBiology.
_968861
650 0 _aMolecular probes.
_969158
650 0 _aArtificial intelligence.
_958441
650 0 _aMolecules
_xModels.
_969914
650 1 4 _aBiological Techniques.
_967847
650 2 4 _aBiological Sciences.
_968865
650 2 4 _aBiological Sensors and Probes.
_969159
650 2 4 _aArtificial Intelligence.
_958441
650 2 4 _aMolecular Modelling.
_969917
700 1 _aSingh, Vijai.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_970653
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9789819774586
776 0 8 _iPrinted edition:
_z9789819774609
776 0 8 _iPrinted edition:
_z9789819774616
856 4 0 _uhttps://doi.org/10.1007/978-981-97-7459-3
912 _aZDB-2-SME
912 _aZDB-2-SXM
999 _c65752
_d65752