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020 _a9789819603015
_9978-981-96-0301-5
024 7 _a10.1007/978-981-96-0301-5
_2doi
050 4 _aQH301-705
072 7 _aPSA
_2bicssc
072 7 _aSCI086000
_2bisacsh
072 7 _aPSA
_2thema
245 1 0 _aSmall Molecules for Cancer Treatment
_h[electronic resource] /
_cedited by Surajit Pathak, Antara Banerjee, Asim K. Duttaroy.
250 _a1st ed. 2024.
264 1 _aSingapore :
_bSpringer Nature Singapore :
_bImprint: Springer,
_c2024.
300 _aXIII, 269 p. 22 illus., 21 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _a1. Small Molecule Therapeutics targeting Ligand-independent activation of Androgen Receptor in Prostate Cancer -- 2. Small molecule targeted compounds for cancer therapy through different pathways -- 3. Exploring small molecule therapies: A comprehensive study on their efficacy in cancer treatment -- 4. Unvailing The Symphony Of Small Molecules In Cutaneous Harmony, Pathophysiology And Regeneration -- 5. Relevance Of Small Molecule Inhibitors in Advancing Cancer Therapeutics -- 6. Application of artificial intelligence in small molecules in cancer therapy -- 7. Role Of Peptides In Oral Cancer -- 8. Innovative Strategies in Cancer Therapy: Overcoming Challenges through Small Molecule and Peptide Design -- 9. Therapeutic Relevance Of Glycosylation Inhibitors In Cancer -- 10. Developments of aptamer-drug conjugates for targeted cancer therapy -- 11. Natural small molecules and their anti-cancer effects -- 12. Small Molecule Inhibitors: Precision Tools Targeting Oncogenic Pathways for Therapeutic Intervention in Cancer -- 13. Small Molecules And Peptides Targetting Tumour Microenvironment.
520 _aThe book explores role of small molecules and peptides in cancer therapy, with a focus on (Aptamer-drug conjugates, Androgen Receptor and Tyrosine Kinase inhibitors, and Glycosylation inhibitors. Small molecule inhibitors targeting oncogenic pathways such as EGFR and PI3K inhibitors, Peptides in oral cancer such as Antimicrobial peptides, Cell Penetrating Peptides, Tumour targeting peptides, Natural small molecules with anti-cancer effects such as phenolic compounds, alkaloids, terpenoids and steroids, Phthalides and lectins, Peptides targeting the tumor microenvironment such as GM-CSF's, LAG3, PD 1, CCL2, CCR-5, CXCR4 inhibitors). An introductory chapter covers the foundation for understanding their significance in cancer treatment. The book delves into the versatility and precision of small molecules, highlighting their advantages in drug delivery and formulation strategies. It emphasizes the expansion of therapeutic horizons through small molecule peptides, shedding light on their potential in targeting tumor microenvironments and advancing cancer therapeutics. Additionally, the book discusses combination therapies and synergistic effects, offering a deeper understanding of integrating different therapeutic approaches. Furthermore, it addresses emerging trends, challenges, safety considerations, and the relevance of small-molecule inhibitors. This book provides a crucial update on the latest advancements and serves as a valuable resource for researchers, clinicians, and students interested in the rapidly evolving landscape of cancer treatment, offering an overview of the potential and complexities associated with these compounds in the fight against cancer.
650 0 _aBiology.
_968861
650 0 _aCancer.
_94311
650 0 _aOncology.
_970760
650 0 _aCancer
_xTreatment.
_963722
650 1 4 _aBiological Sciences.
_968865
650 2 4 _aCancer Biology.
_967829
650 2 4 _aOncology.
_970760
650 2 4 _aCancer Therapy.
_973414
700 1 _aPathak, Surajit.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_975424
700 1 _aBanerjee, Antara.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_975425
700 1 _aDuttaroy, Asim K.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_990571
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9789819603008
776 0 8 _iPrinted edition:
_z9789819603022
776 0 8 _iPrinted edition:
_z9789819603039
856 4 0 _uhttps://doi.org/10.1007/978-981-96-0301-5
912 _aZDB-2-SME
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999 _c66577
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