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020 _a9789819602179
_9978-981-96-0217-9
024 7 _a10.1007/978-981-96-0217-9
_2doi
050 4 _aRC583-598
072 7 _aMJCM1
_2bicssc
072 7 _aMED044000
_2bisacsh
072 7 _aMJCM1
_2thema
245 1 0 _aAsthma-COPD Overlap
_h[electronic resource] :
_bUpdated Concept, Pathophysiology, Diagnosis and Treatment /
_cedited by Hiroyuki Nagase, Hisatoshi Sugiura, Toshihiro Shirai.
250 _a1st ed. 2024.
264 1 _aSingapore :
_bSpringer Nature Singapore :
_bImprint: Springer,
_c2024.
300 _aVIII, 258 p. 23 illus., 18 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aRespiratory Disease Series: Diagnostic Tools and Disease Managements,
_x2509-5560
505 0 _aPart 1 Concept of Asthma COPD overlap -- 1 Concept of Asthma COPD overlap - Japanese guideline and global trends. How was the concept of Asthma COPD overlap developed and moving forward? -- 2 Concept of treatable traits and ACO (2): Can treatable traits approach be applied into practice? -- Part 2 Epidemiology and Prognosis -- 3 Epidemiology of ACO from global data: Does the prevalence of ACO vary among global analyses? -- 4 Epidemiology of ACO defined by the JRS guidelines. What is the prevalence of ACO in Japan? -- 5 Prognosis and characteristics of ACO: What are the specific characteristics of ACO?- 6 Prognosis of COPD with asthma-like features and ACO: Is the prognosis of COPD and ACO different? -- 7 Causes of death in patients with asthma-chronic obstructive pulmonary disease overlap: Is there any difference compared to asthma? -- Part 3 Pathophysiology of ACO -- 8 Inflammatory phenotypes and potential bio-markers of ACO. What is the specific feature of ACO? -- 9 Role of Nitrosative stress: What is the potential clinical implication? -- 10 Radiographic features of ACO. How the feature is applied into practice? -- 11 Pulmonary Function of ACO: What is the role of the forced oscillation technique? -- 12 Underlying mechanism suggested by the ACO model. What is the lesson learned from the model? -- Part 4 Diagnosis of ACO -- 13 Comparison of diagnostic criteria of ACO: What is the point of difference? -- 14 Role of FeNO - How can FeNO be positioned in practice? -- 15 Role of IgE and Eosinophils: The use of type 2 biomarkers in practice -- 16 Rhinosinusitis in ACO: What is the implication of nasal comorbidity? -- Part 5 Treatment -- 17 Current evidence of treatment for asthma-COPD overlap (ACO): Is there emerging evidence of optimal therapy? -- 18 Potential treatment options for ACO, including biologics: Are there any roles of biologics?.
520 _aThis book elucidates the diagnostic criteria and concept of asthma-COPD overlap (ACO) and provides the latest information on its epidemiology, pathophysiology, diagnostic criteria, and treatment options. It discusses the controversy-causing findings of prognosis of ACO, the novel molecular mechanism including nitrosative stress, radiological or physiological features, findings by research that used HRCT or forced oscillation technique. In addition to a recent animal model of ACO, the role of each biomarker, the latest results of ICS/LAMA/LABA combination inhalers or biologics is also debated. Asthma COPD Overlap -Updated Concept, Pathophysiology, Diagnosis, and Treatment is addressed not only to beginners, but also to physicians engaged in clinical practice, supervisors, and many basic researchers. Covering every aspect of ACO, it serves readers to improve diagnosis or treatment for patients with ACO.
650 0 _aAllergy.
_988483
650 0 _aRespiratory organs.
_990788
650 0 _aPhysiology.
_972764
650 0 _aImmunology.
_969214
650 0 _aTherapeutics.
_970087
650 0 _aDiagnosis.
_964942
650 1 4 _aAllergology.
_988484
650 2 4 _aRespiratory Physiology.
_990789
650 2 4 _aImmunology.
_969214
650 2 4 _aTherapeutics.
_970087
650 2 4 _aDiagnosis.
_964942
700 1 _aNagase, Hiroyuki.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_990790
700 1 _aSugiura, Hisatoshi.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_990791
700 1 _aShirai, Toshihiro.
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_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_990792
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
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776 0 8 _iPrinted edition:
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776 0 8 _iPrinted edition:
_z9789819602193
830 0 _aRespiratory Disease Series: Diagnostic Tools and Disease Managements,
_x2509-5560
_990793
856 4 0 _uhttps://doi.org/10.1007/978-981-96-0217-9
912 _aZDB-2-SME
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