000			03992nam a22003854u 4500
001			10.1002/9783527840816
003			Wiley
005			20251030120310.0
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008			240503t2024||||xxu fs| |0|| 0|eng||
020			_a9783527840816 _qelectronic
024	7		_a10.1002/9783527840816 _2doi
041			_aeng
100	1		_aNie, Zhou _4aut _991716
245	1	0	_aDNA Nanotechnology for Cell Research _bFrom Bioanalysis to Biomedicine _h[electronic resource] _cZhou Nie
250			_a1
260			_bWiley _c2024
264		1	_bWiley _c2024
300			_a544pp.;
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _2rdaft
347			_bPDF
520			_aDNA Nanotechnology for Cell Research Comprehensive coverage of DNA nanotechnology with a focus on its biomedical applications in disease diagnosis, gene therapy, and drug delivery Bringing together multidisciplinary aspects of chemical, material, and biological engineering, DNA Nanotechnology for Cell Research: From Bioanalysis to Biomedicine presents an overview of DNA nanotechnology with emphasis on a variety of different applications in cell research and engineering, covering a unique collection of DNA nanotechnology for fundamental research and engineering of living cells, mostly in cellulo and in vivo, for the first time. Broad coverage of this book ranges from pioneering concepts of DNA nanotechnology to cutting-edge reports regarding the use of DNA nanotechnology for fundamental cell science and related biomedical engineering applications in sensing, bioimaging, cell manipulation, gene therapy, and drug delivery. The text is divided into four parts. Part I surveys the progress of functional DNA nanotechnology tools for cellular recognition. Part II illustrates the use of DNA-based biochemical sensors to monitor and image intracellular molecules and processes. Part III examines the use of DNA to regulate biological functions of individual cells. Part IV elucidates the use of DNA nanotechnology for cell-targeted medical applications. Sample topics covered in DNA Nanotechnology for Cell Research include: Selections and applications of functional nucleic acid toolkits, including DNA/RNA aptamers, DNAzymes, and riboswitches, for cellular recognition, metabolite detection, and liquid biopsy. Developing intelligent DNA nanodevices implemented in living cells for amplified cell imaging, smart intracellular sensing, and in cellulo programmable biocomputing. Harnessing dynamic DNA nanotechnology for non-genetic cell membrane engineering, receptor signaling reprogramming, and cellular behavior regulation. Construction of biocompatible nucleic acid nanostructures as precisely controlled vehicles for drug delivery, immunotherapy, and tissue engineering. Providing an up-to-date tutorial style overview along with a highly valuable in-depth perspective, DNA Nanotechnology for Cell Research is an essential resource for the entire DNA-based nanotechnology community, including analytical chemists, biochemists, materials scientists, and bioengineers.
650		4	_aBiomolecules (DNA, RNA, Peptides, etc.) _991323
650		4	_aNanobiotechnology _967632
650		4	_aBiotechnology (Life Sciences) _991129
653	0	0	_acell-cell recognition processes; DNA-based biochemical sensors; image intracellular molecules; regulate biological functions of individual cells; cell-targeted medical applications; gene therapy; drug delivery; membrane engineering
776	0	8	_iPrinted edition: _z9783527351732
856	4	0	_uhttps://doi.org/10.1002/9783527840816 _aWiley Online Library
856	4	0	_uhttps://onlinelibrary.wiley.com/action/showBook?doi=10.1002%2F9783527840816 _aWiley Online Library
856	4	2	_3Cover Image _uhttps://onlinelibrary.wiley.com/cms/asset/63d2599e-d354-44c3-9f85-fbbc254b89a9/9783527840816.cover.gif _aWiley Online Library
999			_c67053 _d67053