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001 10.1002/9781119983347
003 Wiley
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020 _a9781119983347
_qelectronic
024 7 _a10.1002/9781119983347
_2doi
041 _aeng
245 0 0 _aNatural Products and their Bioactives in Antidiabetic Drug Discovery
_h[electronic resource]
_cEdited by Kanti Bhooshan Pandey, Maitree Suttajit, Pinar Atukeren.
250 _a1
260 _bWiley
_c2023
264 1 _bWiley
_c2023
300 _a352pp.;
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_2rdaft
347 _bPDF
520 _aNatural Products and their Bioactives in Antidiabetic Drug Discovery Enables researchers to effectively understand and use bioactive compounds to target, prevent, and manage diabetes Natural Products and Their Bioactives in Antidiabetic Drug Discovery provides readers with an overview of recent research in new drug discovery against diabetic complications based on bioactives from NPs, bridging the gap between the public research institutes and private companies working to find drugs to treat diabetes. To aid in reader comprehension, the text includes case studies and illustrated examples in relevant chapters. Part one presents chapters on fundamental concepts of diabetes mellitus (DM) and recent drug discovery progress along with the various druggable targets and challenges. Part two covers bioactive compounds targeting Type-1 Diabetes. Part three focuses on Type-2 Diabetes. In Part four, the contributors address gestational DM prevention and management with natural compounds. Written by a global team of experts in the field, Natural Products and their Bioactives in Antidiabetic Drug Discovery covers sample topics such as: Obesity risk factor in patients with T1DM and possible role of nutritional therapy in its management Use of natural non-insulin drugs as a novel approach to enhance therapeutic outcomes against T1DM Effectiveness of functional foods in intervening the diabetic complications and realistic results in clinical trials Implementation of nanotechnology in improving the bioavailability and reducing the threshold dose of bioactive compounds Various antidiabetic mechanisms of action of different polyphenols and immunomodulatory role of NPs bioactives relevance in T1DM therapy Effects of natural products on genetics of gestational diabetes With comprehensive coverage of recent research in new drug discovery against diabetic complications based on bioactives from NPs, Natural Products and Their Bioactives in Antidiabetic Drug Discovery is an essential resource for researchers and professionals involved in drug discovery and development, health care, medicinal chemistry, phytochemistry, plant science, and toxicology.
650 4 _aDrug Discovery & Development
_991621
650 4 _aNatural Products
650 4 _aDiabetes
_991303
653 0 0 _adiabetes milletus; diabetes drug discovery; diabetes druggable targets; diabetes challenges; bioactive compounds targeting Type-1 Diabetes; Type-2 Diabetes; diabetes prevention; diabetes management; gestational diabetes
700 1 _aPandey, Kanti Bhooshan
_4edt
_991963
700 1 _aSuttajit, Maitree
_4edt
_991964
700 1 _aAtukeren, Pinar
_4edt
_991965
776 0 8 _iPrinted edition:
_z9781119983316
856 4 0 _uhttps://doi.org/10.1002/9781119983347
_aWiley Online Library
856 4 0 _uhttps://onlinelibrary.wiley.com/action/showBook?doi=10.1002%2F9781119983347
_aWiley Online Library
856 4 2 _3Cover Image
_uhttps://onlinelibrary.wiley.com/cms/asset/b34c2ed3-c7e9-4778-9eae-29aeef8e1db5/9781119983347.cover.gif
_aWiley Online Library
999 _c67166
_d67166