| 000 | 02319nam a22003734u 4500 | ||
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| 001 | 10.1002/9781394264902 | ||
| 003 | Wiley | ||
| 005 | 20251030120317.0 | ||
| 007 | cr nn 008mam|a | ||
| 008 | 231229t2023||||xxu fs| |0|| 0|eng|| | ||
| 020 |
_a9781394264902 _qelectronic |
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| 024 | 7 |
_a10.1002/9781394264902 _2doi |
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| 041 | _aeng | ||
| 100 | 1 |
_aRichard, Guy‐Franck _4aut _992077 |
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| 245 | 1 | 0 |
_aFunction and Evolution of Repeated DNA Sequences _h[electronic resource] _cGuy‐Franck Richard |
| 250 | _a1 | ||
| 260 |
_bWiley _c2023 |
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| 264 | 1 |
_bWiley _c2023 |
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| 300 | _a400pp.; | ||
| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 347 |
_atext file _2rdaft |
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| 347 | _bPDF | ||
| 520 | _aThe genome of a living being is composed of DNA sequences with diverse origins. Beyond single-copy genes, whose product has a biological function that can be inferred by experimentation, certain DNA sequences, present in a large number of copies, escape the most refined approaches aimed at elucidating their precise role. The existence of what 20th century geneticists had already perceived (and wrongly described as "junk DNA"!) was confirmed by the sequencing of the first complex genomes, including that of Homo sapiens. A large part of what defines a living thing is not unique, but repeated, sometimes a very large number of times, increasing in complexity with successive duplications and multiplication. Understanding and defining the many functions of this myriad of repeated sequences, as well as their evolution through natural selection, has become one of the major challenges for 21st century genomics. | ||
| 650 | 4 |
_aBiomolecules (DNA, RNA, Peptides, etc.) _991323 |
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| 650 | 4 |
_aMolecular Biology (Life Sciences) _992078 |
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| 650 | 4 |
_aMolecular Evolution _981053 |
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| 653 | 0 | 0 | _agenome; DNA; DNA sequences; genetics; single-copy genes; junk DNA; repeated DNA sequences |
| 776 | 0 | 8 |
_iPrinted edition: _z9781789451191 |
| 856 | 4 | 0 |
_uhttps://onlinelibrary.wiley.com/action/showBook?doi=10.1002%2F9781394264902 _aWiley Online Library |
| 856 | 4 | 2 |
_3Cover Image _uhttps://onlinelibrary.wiley.com/cms/asset/c965d19f-8af5-49d2-9ad6-9da5f3c74578/9781394264902.cover.gif _aWiley Online Library |
| 999 |
_c67207 _d67207 |
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