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001			10.1002/9781119660699
003			Wiley
005			20251030120317.0
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020			_a9781119660699 _qelectronic
024	7		_a10.1002/9781119660699 _2doi
041			_aeng
245	0	0	_aOral Bioavailability and Drug Delivery _bFrom Basics to Advanced Concepts and Applications _h[electronic resource] _cEdited by Ming Hu, Xiaoling Li.
250			_a1
260			_bWiley _c2023
264		1	_bWiley _c2023
300			_a928pp.;
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _2rdaft
347			_bPDF
520			_aORAL BIOAVAILABILITY AND DRUG DELIVERY Improve the performance and viability of newly-developed and approved drugs with this crucial guide Bioavailability is the parameter which measures the rate and extent to which a drug reaches a user's circulatory system depending on the method of administration. For example, intravenous administration produces a bioavailability of 100%, since the drugs are injected directly into the circulatory system; in the case of oral administration, however, bioavailability can vary widely based on factors which, if not properly understood, can result in a failure in drug development, adverse effects, and other complications. The mechanics of oral bioavailability are therefore critical aspects of drug development. Oral Bioavailability and Drug Delivery provides a comprehensive coverage of this subject as well as its drug development applications. Beginning with basic terminology and fundamental concepts, it provides a thorough understanding of the challenges and barriers to oral bioavailability as well as the possibilities for improving this parameter. The resulting book is an indispensable tool for drug development research. Oral Bioavailability and Drug Delivery readers will also find: Discussion questions in many chapters to facilitate comprehension Detailed discussion of topics including dissolution, absorption, metabolism, and more Real-world examples of methods in actions throughout Oral Bioavailability and Drug Delivery is ideal for pharmaceutical and biotechnology scientists working in drug discovery and development; researchers in chemistry, biology, pharmacology, immunology, neuroscience, and other related fields; and graduate courses in drug development and delivery.
650		4	_aDrug Formulation & Delivery _991495
650		4	_aClinical Pharmacology & Therapeutics _991176
650		4	_aBiochemistry (Chemical Biology) _991082
653	0	0	_aPharmaceutics; pharmacy; drug absorption; drug dissolution; dosage form development; formulation; oral drug delivery; drug metabolism; drug excretion; clinical trials; intravenous bioavailability; silico; biopharmaceutics; drug development; pharmaceutical clinical trials; pharmaceutical research
700	1		_aHu, Ming _4edt _992110
700	1		_aLi, Xiaoling _4edt _992111
776	0	8	_iPrinted edition: _z9781119660651
856	4	0	_uhttps://doi.org/10.1002/9781119660699 _aWiley Online Library
856	4	0	_uhttps://onlinelibrary.wiley.com/action/showBook?doi=10.1002%2F9781119660699 _aWiley Online Library
856	4	2	_3Cover Image _uhttps://onlinelibrary.wiley.com/cms/asset/419966e1-5cf3-4547-85de-3c1cdd0671ba/9781119660699.cover.gif _aWiley Online Library
999			_c67221 _d67221