000 06073cam a22005778i 4500
001 9781003347705
003 FlBoTFG
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006 m o d
007 cr cnu---unuuu
008 230608s2023 flu ob 001 0 eng
040 _aOCoLC-P
_beng
_erda
_cOCoLC-P
020 _a9781003347705
_q(ebook)
020 _a1003347703
020 _a9781000800012
_q(electronic bk. : PDF)
020 _a1000800016
_q(electronic bk. : PDF)
020 _a9781000800067
_q(electronic bk. : EPUB)
020 _a1000800067
_q(electronic bk. : EPUB)
020 _z9781774912775
_q(hardcover)
020 _z9781774912782
_q(paperback)
024 7 _a10.1201/9781003347705
_2doi
035 _a(OCoLC)1381447317
035 _a(OCoLC-P)1381447317
050 0 0 _aRM301.25
072 7 _aMED
_x071000
_2bisacsh
072 7 _aSCI
_x010000
_2bisacsh
072 7 _aMED
_x072000
_2bisacsh
072 7 _aMBGR
_2bicssc
245 0 0 _aDrug repurposing and computational drug discovery :
_bstrategies and advances /
_cedited by Mithun Rudrapal, PhD.
250 _aFirst edition.
264 1 _aPalm Bay, FL, USA ;
_aBurlington, ON, Canada :
_bApple Academic Press ;
_aBoca Raton, FL, USA ;
_aAbingdon, Oxon, UK :
_bCRC Press,
_c2023.
300 _a1 online resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
505 0 _aDrug Repurposing in Future Drug Discovery and Development / Kirti Agrawal, Malavika Saji, and Dhruv Kumar -- Approaches, Strategies, and Advances in Computational Drug Discovery and Drug Repurposing / Tripti Sharma, Ipsa Padhy, and Chita Ranjan Sahoo -- Drug Repurposing and Computational Drug Discovery for Viral Infections and Coronavirus Disease-2019 (COVID-19) / Siddhartha Maji, Vishnu Nayak Badavath, and Swastika Ganguly -- Drug Repurposing and Computational Drug Discovery for Parasitic Diseases and Neglected Tropical Diseases (NTDs) / James H. Zothantluanga, Arpita Paul, Abd. Kakhar Umar, and Dipak Chetia -- Drug Repurposing and Computational Drug Discovery for Malignant Diseases / Ashish Shah, Ghanshyam Parmar, and Ashish Patel -- Drug Repurposing and Computational Drug Discovery for Inflammatory Diseases / Vishal Kumar Singh, Himani Chaurasia, Jayati Dwivedi, Richa Mishra, and Ramendra K Singh -- Drug Repurposing and Computational Drug Discovery for Cardiovascular Disorders / Johra Khan and Mithun Rudrapal -- Drug Repurposing and Computational Drug Discovery for Diabetes / Manish Kumar Tripathi, Rahul Kumar Maurya, Alok Shiomurti Tripathi, and Mohammad Yasir -- Drug Repurposing and Computational Drug Discovery for Aging and Neurological Disorders / Kumar Nallasivan Palani, Karthikeyan Deivasigamani, Sivasubramanian Piramanayagam, and Vishali Murthy -- Challenges and Regulatory Issues in Drug Repurposing and Computational Drug Discovery / Andř M. Oliveira and Mithun Rudrapal.
520 _a"This new volume presents exciting recent advances in drug repurposing and computational approaches for the discovery and development of drugs against certain difficult-to-treat and life-threatening diseases, including microbial infections, parasitic diseases, brain disorders, and cancer. Drug repurposing is defined as identifying new pharmacological indications from old, existing, failed, investigational, already marketed, or FDA approved drugs/pro-drugs, and the application of these newly developed drugs to the treatment of diseases other than the drug's original intended therapeutic use. The application of computational techniques in discovery research does not only help in the development of drugs from leads or existing drug molecules, but also can be of useful for the repurposing of existing drug candidates. This book is primarily aimed at delivering information on various computational techniques, tools, and databases being utilized for drug repurposing and for identifying the uses of existing drug candidates on different emerging or deadly diseases. With contributions from a global team of experts (academicians, scientists, and researchers), this volume, Drug Repurposing and Computational Drug Discovery: Strategies and Advances, explores the sophisticated tools and techniques of drug repurposing and computational drug discovery. It provides up-to-date and in-depth information on the state-of-the-art strategies and techniques being utilized for the discovery of therapeutic candidates from existing natural leads, synthetic compounds, and/or drug molecules by experimental (in vitro, in vivo) as well as computational (in silico) techniques. Drug repurposing and computational approaches addressed in the book target the discovery and development of drugs for microbial infections (bacterial, fungal, viral, COVID-19), parasitic diseases and neglected tropical diseases (NTDs), malignant diseases (cancer), inflammatory diseases, cardiovascular disorders, diabetes, and aging and neurological (CNS) disorders. In addition, the challenges and regulatory issues encountered in drug repurposing and computational drug discovery programs are looked at, offering perspectives for future directions. In addition, the challenges and regulatory issues encountered in drug repurposing and computational drug discovery programs are looked at, offering perspectives for future directions."--
_cProvided by publisher.
588 _aOCLC-licensed vendor bibliographic record.
650 0 _aDrug development.
_984004
650 0 _aDrug development
_xData processing.
_964447
650 0 _aTherapeutics.
_970087
650 7 _aMEDICAL / Pharmacology
_2bisacsh
_964250
650 7 _aSCIENCE / Biotechnology
_2bisacsh
_993035
650 7 _aMEDICAL / Pharmacy
_2bisacsh
700 1 _aRudrapal, Mithun,
_eeditor.
_993811
856 4 0 _3Taylor & Francis
_uhttps://www.taylorfrancis.com/books/9781003347705
856 4 2 _3OCLC metadata license agreement
_uhttp://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf
942 _cE-Books
999 _c67640
_d67640